<![CDATA[Sunscreen test of keledang (Artocarpus lanceifolius Roxb.) leaves based on in vitro method was carried out. This research aimed to investigate the property of sunscreen from methanol extract, n-hexane, ethyl acetate and methanol-water fraction of keledang leaves. The methods used include the in vitro methods by using spectrophotometer UV-Vis. Based on results of phytochemical test, it was known that methanol extract contains flavonoids, phenolics, steroids/triterpenoids. n-Hexane fraction contains steroids/triterpenoids and quinones. Ethyl acetate fraction contains flavonoids, phenolics, steroids/triterpenoids and quinones. Methanol-water fraction contains flavonoids and phenolics. Methanol extract, n-hexane, ethyl acetate and methanol-water fraction also showed sunscreen activity based on the SPF value at a concentration of 25; 50; 100; 150; 200 and 250 mg/L. Crude methanol extract has SPF value respectively were 4.44; 7.36; 15.15; 22.47; 31.25 and 37.31 (minimum-ultra). N-Hexane fraction has SPF value respectively were 1.37; 2.24; 5.07; 7.51; 10.01 and 12.74 (minimum-maximum). Ethyl acetate fraction has SPF value respectively were 3.321; 7.20; 13.03; 19.54; 25.97 and 30.59 (minimum-ultra). Methanol-water fraction has SPF value respectively were 5.24; 10.87; 21.48; 30.89; 36.01 and 38.52 (medium-ultra). The SPF value increases with increasing concentration because the higher the concentration, the more active sunscreen compounds contained in the extract and fraction. In keledang leaves, methanol-water fraction has the highest suncreen activity folowed by methanol extract, ethyl acetate fraction and n-hexane fraction. Keledang leaves have a potency as sunscreen agent. Keywords: Artocarpus lanceifolius; in vitro; sunscreen]]>
