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All Journal Dentino: Jurnal Kedokteran Gigi Yarsi Dental Journal
Sinar Yani
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Dentistry

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UJI IRITASI PADA KASUS PERIODONTITIS MODEL TIKUS WISTAR SETELAH APLIKASI EKSTRAK SARANG SEMUT Lilies Anggarwati Astuti; Ika fikriah; Sinar yani
YARSI Dental Journal Vol. 2 No. 1 (2024): YARSI DENTAL JOURNAL
Publisher : Lembaga Penelitian Universitas YARSI

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Abstract

Introduction: Infected periodontal pocket by microorganisms plays an important role in the occurrence of periodontal tissue necrosis and the formation of periapical abnormalities. Therefore, periodontal pocket treatment should be carried out with the aim of eliminating or reducing the microbial population and biomechanically removing necrotic tissue which is a medium for microbial growth and preventing re-infection. One of the medicinal plants from the Kalimantan forest that has great potential is Sarang Semut (Myrmecodia pendens). (12) Objective: This study aims to determine the response of gingival healing in the case of periodontitis in the Wistar rat model after the application of Sarang Semut (Myrmecodia pendens) extract. Material and Methods: Sarang Semut (Myrmecodia pendens) extract dilution to concentration of 2.5%, 5% and 10% was carried. This research is a laboratory experimental research and used post-test with control group design. Results: There are three concentrations that have been given: 2.5%, 5%, and 10%. The smallest concentration provides a healing area. Discussion: The results showed that ethanol extract of Sarang Semut can increase the healing response of the gingiva that has been induced by periodontitis bacteria. Conclusion: Gingival healing response in periodontitis case of Wistar rat model after application of Sarang Semut extract (Myrmecodia pendens) showed results similar to positive control on 2.5% Sarang Semut extract application. Clinical signs on the rat's gingiva that experienced discoloration, countours and bleeding on the 3rd day gradually improved and on the 7th day there was no pocket depth.
ANTIBACTERIAL ACTIVITY TEST OF CUCUMBER PEEL EXTRACT (Cucumis sativus L.) AGAINST Streptococcus mutans BACTERIA Rahmalia Dewi; Masyhudi Masyhudi; Alhawaris Alhawaris; Sinar Yani; Yadi Yadi
Dentino: Jurnal Kedokteran Gigi Vol 9, No 1 (2024)
Publisher : FKG ULM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v9i1.18869

Abstract

Background: Dental caries is a  process of tooth demineralization caused by acids produced from food metabolism in bacteria. One of the main etiological factors of dental caries is the microorganisms known as Streptococcus mutans bacteria. S. mutans is one of the components of human dental plaque that is associated with sucrose diet and high caries activity. Cucumber peel extract (Cucumis sativus L.) is known to have an antibacterial activity due to the presence of secondary metabolites such as flavonoids, steroids, alkaloids, saponins and phenols found in cucumber peel. Purpose: This study aimed to determine the antibacterial activity at the lowest concentration of cucumber peel extract (Cucumis sativus L.) against Streptococcus mutans bacteria. Method: This study employed the disc diffusion method with a post-test only control group design. Streptococcus mutans bacteria were cultured on Mueller Hinton Agar media, and cucumber peel extract (Cucumis sativus L.) was applied as the antibacterial agent at concentrations of 0.01 g/ml, 0.05 g/ml, 0.1 g/ml, 0.2 g/ml, 0.4 g/ml and 0.5 g/ml with seven repetitions. Results: The results of the study showed that cucumber peel extract (Cucumis sativus L.) formed inhibition zones around the paper discs against the growth of Streptococcus mutans bacteria at concentrations of 0.4 g/ml and 0.5 g/ml. Conclusion: The concentrations of 0,4 g/ml and 0,5 g/ml are the lowest concentrations of cucumber peel extract (Cucumis sativus L.) that can inhibit the growth of Streptococcus mutans bacteria. Keywords : Antibacterial, Cucumber peel, Dental Caries, Streptococcus mutans
Co-Authors Alhawaris Alhawaris Endang Sawitri Fikriah, Ika Lilies Anggarwati Astuti Masyhudi Masyhudi Musnar Munir Rahmalia Dewi Riries Khoiru Sulistiani, Dewi Yadi Yadi