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TINGKAT PEMAHAMAN DAN FAKTOR KEPATUHAN MINUM OBAT ARV PADA PASIEN HIV/AIDS Adib Samudra Putra; Saepuddin Saepuddin; Suci Hanifah
Parapemikir : Jurnal Ilmiah Farmasi Vol 12, No 3 (2023): Parapemikir : Jurnal Ilmiah Farmasi
Publisher : Pusat Penelitian dan Pengabdian Masyarakat Politeknik Harapan Bersama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30591/pjif.v12i3.5298

Abstract

Patients with HIV/AIDS require long-term therapy, so adherence is a significant thing that needs attention. aim  of this article review is to find out the Level of Understanding and Compliance Factors in Taking ARV Medication in HIV/AIDS Patients. The research was conducted in November 2022 by searching for Indonesian articles related to article reviews with the year of publication 2017-2022 in the Google scholar database using the keyword "HIV/ AIDS”, “adherence to taking ARV medication”, and “HIV understanding. Then found 15 journals related to understanding and factors that influence adherence to taking ARV medication with the correlative analytic research method with a cross sectional approach. After further evaluation, 7 relevant journals were found. Next is done by analysis with the approach. A person's understanding of HIV/AIDS is not influenced by their level of education. Family and social support affects the level of patient adherence to routinely taking ARV drugs. Intensive counseling needs to be given to patients and their families as well as the social environment so that patients with HIV/AIDS can be more compliant in using ARV therapy
Nature of Precipitation Resulted from Intravenous Drugs Incompatibility Suci Hanifah; Patrick A. Ball; Ross A. Kennedy
ASEAN Journal for Science and Engineering in Materials Vol 4, No 2 (2025): AJSEM: Volume 4, Issue 2, September 2025
Publisher : Bumi Publikasi Nusantara

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Abstract

In critical care, the co-administration of intravenous drugs often leads to physical incompatibilities, resulting in harmful precipitates. This study evaluated the nature of drug-induced precipitation in terms of size, shape, and quantity. Twelve drugs previously reported to be incompatible were tested with infusion fluids. Particle detection was conducted using an Olympus CX41 microscope with a 1 µm detection limit, enhanced by darkfield microscopy for better sensitivity. Particle size was analyzed using Feret’s diameter via the Optilab imaging system. Precipitates ranged from 5–150 µm, with smaller particles (<10 µm) seen in furosemide and subvisible particles (10–50 µm) in cefotaxime, chloramphenicol, and paracetamol. Visible particles were noted in acyclovir, ampicillin, meropenem, phenobarbital, and phenytoin. Most macro-precipitates were acicular, while micro-precipitates tended to be irregular. Particle counts ranged from 80 to 2,000 particles/mL. The findings highlight the clinical risk of particulate contamination due to drug incompatibilities, emphasizing the need for careful medication management.