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All Journal Journal of Research in Pharmacy and Pharmaceutical Sciences
Imam Prabowo
Program Studi Farmasi Program Sarjana FK UPN Veteran Jakarta
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Other

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LITERATURE REVIEW: GREEN TEA EXTRACT POTENCY (Camellia sinensis) in LOWERING GLYCEMIC INDEX OF A WISTAR RAT Filda Nisrina Fajrin; Imam Prabowo; Lisa Safira
Journal of Research in Pharmacy and Pharmaceutical Sciences Vol 1 No 2 (2022): Vol.1 No.2 DECEMBER (2022)
Publisher : Pharmacy Program, Faculty of Medicine, UPN Veteran Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jrpps.v1i2.5162

Abstract

 The aim of the research is to determine the potency of green tea extract (Camellia sinesis) to decrease blood glucose levels in diabetes mellitus model Wistar rats. A systematic review based on PRISMA-P 2020 with a literature search strategy using Google Scholar, PubMed, Science Direct, and Scopus databases. Literature quality was assessed using the JBI Critical Appraisal Checklist which produced 12 comprehensive potential literatures based on selection with inclusion and exclusion criteria. Analysis of 12 journals found that there were 11 studies that showed a significant decrease in blood glucose levels after administration of green tea extract (Camellia sinensis). Green tea extract (Camellia sinensis) has the potential to reduce blood glucose levels in Wistar strain rats with diabetes mellitus model. The mechanism underlying the antihyperglycemic effect is proven to be due to the protective and antidiabetic effects of the compounds contained in green tea extract, especially the flavonoid group, namely catechins. The minimum dose of green tea extract observed to cause an antihyperglycemic effect in experimental animals was 40 mg/kgBW.
COMPARISON OF THE ANTIMICROBIAL EFFECTIVENESS OF GARLIC EXTRACT AND THE ANTIBIOTIC CLINDAMYCIN ON THE GROWTH OF THE BACTERIA PROPIONIBACTERIUM ACNES AND STAPHYLOCOCCUS EPIDERMIDIS Imam Prabowo; Daniel Natanael Malona; Oktania Sandra Puspita
Journal of Research in Pharmacy and Pharmaceutical Sciences Vol 2 No 2 (2023): Vol.2 No.2 DECEMBER (2023)
Publisher : Pharmacy Program, Faculty of Medicine, UPN Veteran Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jrpps.v2i2.7182

Abstract

Acne vulgaris is an inflammatory disorder of pilosebaceous glands caused by an increase in sebum production, abnormal follicle keratinization, and colonization of positive gram P. acnes and S. epidermidis bacteria. Clindamycin antibiotic resistance has been reported because it is used to bacteria that cause acne vulgaris. Garlic extract has antimicrobial properties called allicin. This study aimed to determine the in vitro antimicrobial effectiveness of garlic extract in the growth of P. acnes and S. epidermidis. The samples of this study are garlic extract. This study was a true experimental study conducted using disc diffusion method with Mueller Hinton Agar. The zone of inhibition was observed on all groups of P. acnes and S. epidermidis in all tested concentrations with allicin concentration of 256µg/ml showing the widest zone of inhibition. Statistical analysis using the One- Way ANOVA resulted in (p)<0.005. Conclusively, garlic extract was effective in inhibiting the growth of P. acnes and S. epidermidis.
Co-Authors Daniel Natanael Malona Filda Nisrina Fajrin Lisa Safira Oktania Sandra Puspita