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Rini Andriani
SMF Neurologi Pusat Kanker Nasional RS Dharmais, Jakarta

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PREVALENSI NYERI NEUROPATIK PADA PASIEN DENGAN NYERI KANKER DI RSUPN DR CIPTO MANGUNKUSUMO DAN PKN RS DHARMAIS Henry Riyanto Sofyan; Tiara Aninditha; Louis Kwandou; Jonathan Odilo; Rini Andriani
NEURONA Vol 37 No 3 (2020)
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v37i3.160

Abstract

Introduction: Cancer pain is one of the most common complications in cancer. As much as 30-50% of cancer patients experienced pain. Cancer pain patients have reported complaints of pain with a neuropathic component. Early diagnosis of neuropathic cancer pain has a clinical implication for patient management. However, the proportion of neuropathic cancer pain has not been studied in Indonesian population. Aim: The study was to get an overview of neuropathic pain prevalence among cancer pain patients in Cipto Mangunkusumo General Hospital and National Cancer Referral Dharmais Hospital. Methods: The design of this research was cross-sectional. The study was done in Cipto Mangunkusumo General Hospital and National Cancer Referral Dharmais Hospital in July-September 2019. The subjects in this research were adult cancer patients who consulted with the Department of Neurology. The data acquired were patient’s demography, cancer history, imaging, and pain assessment. PainDETECT questionnaire was employed to assess neuropathic pain. The data were processed and presented descriptively and analytically. Results: There were 57 subjects obtained in this research with average age of 45.91. As much as 31.6% subjects had neuropathic cancer pain. Breast cancer identified in 38.6% subjects. There were no differences of gender, age, cancer type, and pain intensity between subjects with and without neuropathic cancer pain. Radiating pain and subject with metastasis experienced neuropathic cancer pain more frequently. Discussion: The prevalence of neuropathic cancer pain in the Indonesian population is 31.6%. Radiating pain and patients with metastasis cancer tend to experienced neuropathic pain more frequently. Keywords: Cancer, Indonesia, neuropathic pain, prevalence
KARAKTERISTIK METASTASIS SISTEM SARAF PUSAT DARI KANKER PARU Tan Yosephine; Tiara Aninditha; Henry Riyanto Sofyan; Jonathan Odilo; Rini Andriani
NEURONA Vol 37 No 4 (2020)
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v37i4.174

Abstract

Introduction: As much as 40% of lung cancer patients will experience central nervous system (CNS) metastasis in the course of the disease. From those 40%, as much as 3-9% will experience leptomeningeal metastasis, but the clinical profile of CNS involvement in lung cancer has never been studied before in Indonesia. Aim: To give a description of CNS metastasis from lung cancer inCipto Mangunkusumo General Hospital and National Cancer Referral Dharmais Hospital. Methods: This is a cross-sectional study done in patients consulted to Neurology Department inCipto Mangunkusumo General Hospital and National Cancer Referral Dharmais Hospital in 2018. Inclusion cirteria is adult patients diagnosed with lung cancer based on histopathology with complete medical record to the extent of CT scan or Head MRI with contrast. Results: There were 48 subjects with median age of 57 (36-76) years, men were more than women (56.2% vs 44.8%) and 31.3% had history of smoking. The most frequent lung cancer type is non-small cell lung cancer (NSCLC) (93,8%). Neurological symptoms found were motoric deficits (62.5%), headache (43.8%), cognitive dysfunction (20.8%), and seizure (18.8%). Majority of subjects suffered from brain metastasis (93.8%) and 8.3% were leptomeningeal metastasis. Discussion: The majority of CNS metastasis were brain metastasis from NSCLC (93.8%) with main neurological deficits were motoric deficits (62.5%) and headache (43.8%). Keywords: Brain metastasis, lung cancer, non-small cell lung carcinoma