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Ikhlas Taufik
Fakultas Kedokteran Universitas Lampung
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Penggunaan Klinis Substansi Bioaktif Nigella sativa (Jintan Hitam) sebagai Alternatif Pengobatan Diabetes Mellitus Tipe 2 Ikhlas Taufik
MAJORITY Vol 9 No 2 (2020): MAJORITY
Publisher : Majority

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Abstract

Diabetes Mellitus is a metabolic disorder characterized by hyperglycemia caused by deficiency of insulin production, decreased insulin function, or both. There are two main forms of Diabetes Mellitus, Insulin-Dependent Diabetes Mellitus (Type 1 DM) or Non Insulin Dependent Diabetes Mellitus (Type 2 DM). Insulin is a hormone produced by the pancreas gland and transport glucose from the bloodstream to body cells. Lack of insulin production or the inability of cells to respond insulin cause high blood glucose levels or Hyperglicemia which can lead to complication and organ failure. Management of Type 2 Diabetes Mellitus has been carried out by pharmacological, nutritional, lifestyle modification, and complement therapy. So far, effective therapeutic methods have been developed to prevent and resolve Type 2 Diabetes Mellitus, one of which is by utilizing ethnobotany or herbal plants such a black cumin or Nigella sativa in Latin. Several studies have stated that Nigella sativa (NS) is a bioactive substance that has a therapeutic effect on the metabolic parameters of Type 2 Diabetes Mellitus. Further studies are needed to determine its potential as a supplement for preventive efforts and herbal therapy for Type 2 Diabetes Mellitus.
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