Article Per Year (5 Year)
p-Index From 2021 - 2026
0.23
P-Index
This Author published in this journals
All Journal Majority
Muhartono
Bagian Patologi Anatomi, Fakultas Kedokteran, Universitas Lampung
Education Health Professions Medicine & Pharmacology Public Health

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
Pengaruh Ekstrak Etanol Buah Belimbing Wuluh (Averrhoa Bilimbi L.) Sebagai Antioksidan Terhadap Histopatologi Hepar Tikus Putih (Rattus Novergicus) Galur Wistar Yang Diinduksi Minyak Jelantah Stefani Agustin Parapasan; Muhartono; Muhammad Iqbal; Asep Sukohar
MAJORITY Vol 11 No 2 (2023): MAJORITY
Publisher : Majority

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Used cooking oil can damage hepatic cell because of free radicals. Averrhoa bilimbi L. contains flavonoid and other active compounds as antioxidants in reducing liver cell damaged due to used cooking oil. This research aims to determine the effect of ethanol extract of Averrhoa bilimbi L. on the liver histopathology of white rats (Rattus novergicus) Wistar strain induced by used cooking oil. This research is a laboratory experimental research with a Post Test-Only Control Group Design approach. Research using 25 rats which divided into 5 groups, namely K1 (aquades), K2 (used cooking oil), P1, P2, P3 given used cooking oil at a dose of 1,5 mL and extract with different doses (80 mg, 160 mg, and 320 mg) for 28 days. The mean scoring histopathological damage to the white rat’s liver at K1= 1,08±0,11; K2 = 3,08±0,18; P1 = 2,64±0,49; P2 = 2,32±0,26; P3 = 1,8±0,14. Research using Kruskal-Wallis test (p<0,05) followed by the Post-hoc Mann Whitney test (p<0,05). There is an effect  of ethanol extract of Averrhoa bilimbi L. as an antioxidant on the liver histopathology of white rats (Rattus novergicus) Wistar strain induced by used cooking oil.
Co-Authors Asep Sukohar Muhammad Iqbal Stefani Agustin Parapasan