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All Journal The Journal General Health and Pharmaceutical Sciences Research Jurnal Implementa Husada (JIH)
Hasroni Fathurrahman
Universitas Muhammadiyah Sumatera Utara
Health Professions Nursing Other

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Keterkaitan Volume Prostat dengan Skor IPSS pada Penderita Benign Prostatic Hyperplasia (BPH) di RSU Haji Medan Jihan Maghfira; Hasroni Fathurrahman; Aril Rizaldi
The Journal General Health and Pharmaceutical Sciences Research Vol. 2 No. 4 (2024): December : The Journal General Health and Pharmaceutical Sciences Research
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/tjghpsr.v2i4.474

Abstract

Benign prostatic hyperplasia (BPH) is a benign neoplasm characterized by hyperplasia in the periurethral area of the prostate. This condition often causes lower urinary tract symptoms (LUTS) that can interfere with daily activities although rarely life-threatening. Prostate volume is an important indicator to assess the severity, progressivity of the disease, as well as response to treatment. The International Prostate Symptom Score (IPSS) questionnaire is used to measure the severity of LUTS symptoms. This study aimed to evaluate the relationship between prostate volume and IPSS score in BPH patients at RSU Haji Medan. This study used a retrospective analytic observational design with a cross-sectional approach. Samples were selected based on inclusion and exclusion criteria, with data taken from BPH patients in the urology department of RSU Haji Medan during the period September to December. Analysis was performed using Spearman correlation test. Of the 93 samples, the highest incidence of BPH was found in the age group of 61-70 years (43.0%). Most prostate volume was in classification 1 (20-39 cc) with 53 people (57.0%), while the most frequent degree of symptoms was severe degree (high IPSS) with 39 people (41.9%). Spearman correlation test showed a significant association between prostate volume and IPSS score (p < 0.001), with a very strong positive correlation coefficient (r = 0.853), indicating a unidirectional relationship. Prostate volume has a significant relationship with IPSS score in patients with Benign Prostatic Hyperplasia (BPH). This finding underscores the importance of prostate volume measurement in assessing symptom severity and determining treatment strategies.
Higher Body Mass Index Correlates with Increased Tumor Aggressiveness in Prostate Adenocarcinoma: Evidence From a Hospital-Based Cross-Sectional Study Adam Yulianto; Hasroni Fathurrahman
JURNAL IMPLEMENTA HUSADA Vol 7, No 1 (2026)
Publisher : UMSU

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/jih.v7i1.26870

Abstract

Prostate cancer remains a major cause of cancer-related mortality in men and represents the most common urological malignancy. Age and obesity have long been recognized as important risk factors that may shape both tumor differentiation and progression. The Gleason scoring system, used to grade prostate adenocarcinoma, captures how differentiated the tumor cells are and helps estimate its level of aggressiveness. This study aimed to evaluate the association between age and BMI with the histopathological grade of prostate adenocarcinoma at Dr. Pirngadi General Hospital Medan. A cross-sectional analytical study was conducted using secondary data from medical records of 70 patients diagnosed with prostate adenocarcinoma. Statistical analysis was performed using Spearman’s correlation test. The results showed that 6 patients (8.6%) were aged 60 years, 41 patients (58.6%) had BMI ≥23 kg/m², and 28 patients (40%) presented with Gleason scores of 8–10. There was no statistically significant association between age and histopathological grade (p = 0.571). A statistically significant but weak positive correlation was identified between BMI and histopathological grade (p = 0.003, r = 0.347). These findings indicate that BMI may influence the degree of tumor differentiation and should be considered in the pathological and clinical evaluation of prostate cancer.
Co-Authors Adam Yulianto ARIL RIZALDI Jihan Maghfira