Dharma Permana
Departement of Pharmacology, Faculty of Medicine, Yarsi University, Jakarta Pusat 10510

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Use of Antibiotics for acute respiratory infection (ARI) in Puskesmas Karang Rejo, Tarakan Mirza Insani; Dharma Permana
Yarsi Journal of Pharmacology Vol. 1 No. 1 (2020): January 2020
Publisher : Bagian Farmakologi, Fakultas Kedokteran Universitas YARSI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33476/yjp.v1i1.1208

Abstract

Background: Acute respiratory infection (ARI) is a serious infection that prevents normal breathing function. It usually begins as a viral infection in the nose, trachea (windpipe), or lungs. If the infection is not treated, it can spread to the entire respiratory system. ARI prevents the body from getting oxygen and can result in death. ARI is the most common diagnosis for which antibiotics are prescribed and there are many reasons why primary care doctors prescribe antibiotics. The aim of this study was to know the use of antibiotic drugs in ARI patients at Puskesmas Karang Rejo, Tarakan.Methods: The research method is a descriptive with retrospective data collection by collecting secondary data obtained from medical records at Puskesmas Karang RejoTarakan in the period of January-April 2017. Results: A total of 595 medical records were selected, there were 58.66% (n = 349) female and 41.34 % (n = 246) male, and most occurred in children aged 1-5 years 31.60% (n=188) and aged 6 -10 years 20.84% (n=124). The most common types of ARI were acute tonsillitis 33.61% (n=200), nonspecific respiratory tract infection 32.77% (n=195) and pneumonia 13,94% (n=83. The antibiotic drugs used were amoxicillin 73.11% (n=435), cotrimoxazole 22.02% (n=131), ciprofloxacin 2.52% (n=15), cephadroxil 1.68% (n=10) and chloramphenicol  0.67% (n=4). Amoxicillin and cotrimoxazole were the most commonly used antibiotic for treatment of patients with all types of ARI. Amoxicillin use was highest in acute tonsillitis (94.00%, n=188) and nonspecific respiratory tract infection (85.13%, n=166), while cotrimoxazole use was highest in pneumonia (90.36%, n=75).Conclusion: Amoxicillin and cotrimoxazole were the mostly used antibiotics for treatment of patients with ARI in Puskesmas Karang Rejo, Tarakan.
The use of antihypertensive drugs in the treatment of essential hypertension at outpatient installations, Puskesmas Karang Rejo, Tarakan Salma Nara Fadhilla; Dharma Permana
Yarsi Journal of Pharmacology Vol. 1 No. 1 (2020): January 2020
Publisher : Bagian Farmakologi, Fakultas Kedokteran Universitas YARSI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33476/yjp.v1i1.1209

Abstract

Background: Essential hypertension is the most common type of hypertension, affecting 95% of hypertensive patients. Essential hypertension can be managed through a combination lifestyle changes and antihypertensive drugs. The aim of this study was to know the use of antihypertensive drugs in the treatment of essential hypertensive at outpatient installations, Puskesmas Karang Rejo, Tarakan.Methods: The research method is descriptive by using secondary data from complete patient medical records of the essential hypertension patients undergoing outpatient treatment at Puskesmas Karang Rejo, Tarakan in the period of January-April 2017.Results: A total of 557 medical records were selected, there were 72.53% (n = 404) female and 27.47 % (n = 153) male; age ranged from 20-80 years (mean = 50.32 years). The most common of essensial hypertension were 47.22 % (n = 263) grade II hypertension and 45.42 % (n = 253) grade I hypertension. The antihypertensive drugs were used single or in combination in the following order: Amlodipine (Calcium channel blockers), Captopril (ACE inhibitors), Hydrochlorothiazide/HCT (Diuretic), Methyldopa (alpha-2 adrenergic receptor agonist) and Isosorbid dinitrate (Vasodilator). Four hundred fifty four (81.51%) patients were treated with a single drug (monotherapy) and 103 (18.49%) patients were given combination therapy. Monotherapy and the combination of two antihypertensive drugs were used for prehypertension, grade I hypertension and grade II hypertension, with the most widely used drugs as monotherapy was amlodipine (67.86%, n =378 ) and the mostly used combination therapy of two antihypertensive drugs was Amlodipine-Hydrochlorothiazide (15.80%, n = 88).  The combination of antihypertensive Amlodipin-Hydrochlorothiazide-Captopril (0.35%, n=2) was used for hypertension grade II.Conclusion: Amlodipine was the most widely used drug as monotherapy or combination drugs therapy in the treatment of essensial hypertension at outpatient installations, Puskesmas Karang Rejo.