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All Journal JENGGALA: Jurnal Riset Pengembangan dan Pelayanan Kesehatan ASSYIFA: Jurnal Ilmu Kesehatan
Yusnita Julyarni Akri
Politeknik Kesehatan Wira Husada Nusantara Malang
Dentistry Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

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POTENSI TANAMAN OBAT INDONESIA ATASI TUMOR DAN KANKER: TINJAUAN SISTEMATIS: The Potential of Indonesian Medicinal Plants to Overcome Tumors and Cancer: A Systematic Review Yusnita Julyarni Akri
ASSYIFA : Jurnal Ilmu Kesehatan Vol. 2 No. 2 (2024)
Publisher : Forind Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62085/ajk.v2i2.78

Abstract

Indonesia with very high biodiversity has great potential for the development of drugs from natural products. The use of traditional medicine in treatment efforts continues to increase, the design of this study is a systematic review. The search for the articles discussed in this study uses several databases, including Pubmed, Proquest, and ScienceDirect, with a time span of 2014 to 2024. The keywords used to search for the article are medicinal plants, tumors, cancer, and anticancer. The type of article used is a research article. The collected articles are then re-selected using inclusion criteria, namely: 1) the purpose of the article is to analyze the potential of medicinal plants as anticancer, 2) it is an experimental research, and the exclusion criteria, namely 1) it is not a full-text article, 2) the article does not use Indonesian or English. Based on the 6 selected articles, there are several plants that have the potential to cure cancer. These plants have been scientifically tested to have active compounds that can kill cancer cells.
Pengaruh Kortikosteroid Terhadap Kontrol Glikemik Pasien Diabetes Mellitus Tipe 2: Systematic Review Yusnita Julyarni Akri; Donna Dwinita Adelia; Donny n Yunamawan; Yanuar Hadi Irawan
Jenggala : Jurnal Riset Pengembangan dan Pelayanan Kesehatan Vol 5 No 1 (2026): JUNI 2026
Publisher : Fakultas Teknologi dan Manajemen Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56399/jgl.v5i1.398

Abstract

Corticosteroids are widely used drugs in a variety of clinical conditions and are known to affect glucose metabolism through increased gluconeogenesis and insulin resistance. In patients with Type 2 Diabetes Mellitus (DMT2), corticosteroid use has the potential to worsen glycemic control and increase the risk of hyperglycemia. However, the scientific evidence regarding the effect of corticosteroids on glycemic control in DMT2 patients is still scattered and varied, so a systematic review is needed. This systematic review aimed to evaluate the effect of corticosteroid use on glycemic control in DMT2 patients based on a narrative synthesis of available research results. Literature searches were conducted systematically on electronic databases PubMed, Scopus, ScienceDirect, and Google Scholar. The included studies included observational and experimental studies involving DMT2 patients receiving corticosteroid therapy, with outputs in the form of glycemic control parameters such as fasting blood glucose, postprandial blood glucose, and HbA1c. The selection of studies is carried out based on the inclusion and exclusion criteria that have been set. The methodological quality assessment of the study was carried out using relevant instruments, and the research results were synthesized narratively following the PRISMA guidelines. Most of the studies reviewed showed an increase in blood glucose levels and/or HbA1c in patients taking corticosteroids, particularly in the use of systemic corticosteroids with specific doses and durations. The variation in effects on glycemic control was influenced by the type of corticosteroid, route of administration, duration of therapy, and clinical characteristics of the patient. Some studies have also reported an increased need for antidiabetic therapy during corticosteroid use. Based on narrative synthesis, corticosteroid use tends to negatively impact glycemic control in Type 2 Diabetes Mellitus patients.
Co-Authors Donna Dwinita Adelia Donny n Yunamawan Yanuar Hadi Irawan