Horiuchi, Yasuhiro
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Agapanthus allergic contact dermatitis: A case report Horiuchi, Yasuhiro
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 8, No. 1
Publisher : UI Scholars Hub

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Background: Agapanthus (Lily of the Nile) is a genus in the flowering plant family Amaryllidaceae. Contact dermatitis caused by flowering plants is common, but there are no reports of contact dermatitis caused by this plant, Agapanthus. Case Illustration: An 82-year-old Japanese man had cultivated Agapanthus in his home garden. After breaking the stem of the leaf while wearing shorts, he noticed erythematous rashes on the thighs. The patch test of the leaf stem sap “as is” showed mildly positive, with erythematous papules. Discussion: The patch test confirmed the allergic contact dermatitis of Agapanthus with leaf stem sap. There are many well-known flowering plants, like lilies, daisies, jasmine, orchids so on, that can cause contact dermatitis. To date, many people fold Agapanthus flowers and decorate them at home, so far, this plant should also be added to the causative plant for contact dermatitis. Conclusion: To the best of our knowledge, there are no reports of contact dermatitis caused by this plant. Agapanthus contact dermatitis will need to be brought to people’s attention.
Onycholysis in an elderly woman: Proposal for treatment with Coix seed extract administration Horiuchi, Yasuhiro
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 8, No. 2
Publisher : UI Scholars Hub

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Background: The exact etiology of onycholysis, which is characterized by the painless separation of the nail from the nail bed, remains unclear. Currently, there are no established effective treatments for this condition. Coix seed extract (C-S extract), a traditional Chinese medicine, is recognized for its various biological properties. Case Illustration: This report describes a case of onycholysis affecting the left index finger of a 62-year-old female patient, with initial symptoms appearing three months prior. Despite ongoing internal administration of C-S extract, the patient experienced a recurrence of onycholysis on both the index finger and pinky finger of the left hand a few months later. Notably, both the initial occurrence and the relapse were resolved with the use of oral C-S extract. Discussion: C-S extract is commonly utilized in both medicinal and cosmetic application; however, its underlying biological mechanism remain largely unexplored. It has been suggested that the extract may serve as an effective anti-aging agent for the skin. Nonetheless, it is perceived that the potency of C-S extract is relatively limited. Conclusion: Therefore, further scientific evaluation of the biological function of C-S extract is warranted. While it shows promise as an anti-aging agent and has a favorable safety profile, its overall efficacy appears to be moderate.