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All Journal Catimore: Jurnal Pengabdian Kepada Masyarakat Jurnal Penyakit Dalam Indonesia
Pangestu, Andhika
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Education Environmental Science Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Social Sciences Other

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Efektivitas dan Keamanan Beraprost untuk Pengobatan Klaudikasio Intermiten pada Critical Limb Threatening Ischemia (CLTI) Pangestu, Andhika; Asicha, Nur; Cahyanur, Rahmat; Resultanti, Resultanti
Jurnal Penyakit Dalam Indonesia Vol. 10, No. 2
Publisher : UI Scholars Hub

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Abstract

Critical limb threatening ischemia (CLTI) is the most advanced stage of peripheral arterial diseases. Alternative treatment for claudication in CLTI patients is beraprost. We aim to review effectiveness and safety beraprost for relieve symptoms in CLTI. We conducted systematic literature searching using PubMed/MEDLINE, Embase, ProQuest, and Cochrane databases. Selected articles were examined for duplication and screened by abstract and title. Then, we appraised the articles based on the critical appraisal sheet from Centre for Evidence-Based Medicine (CEBM) University of Oxford. We found one systematic review-meta analysis (SR-MA) which involved 4,477 randomized participants. The results from this study are moderate quality evidence that prostanoids reduced rest pain (RR 1.30; 95%CI 1.06 – 1.59) and promoted ulcer healing (RR 1.24; 95%CI 1.04 – 1.48). In adult patients with CLTI and intermittent claudication as the primary complaint, vasodilator agents such as beraprost have a beneficial effect and a favorable therapeutic response. Numerous effects, including cardiovascular benefit, adverse events, resting pain relief, ulcer healing, outcome maximum walking distance (MWD), and pain-free walking distance, demonstrate the benefit (PFWD). The benefits of beraprost differ depending on the mechanism of action and pharmacokinetics of the drugs.
Inovasi Olahan Pepaya Lokal untuk Mendukung Ekonomi Rumah Tangga di Desa Ciampanan Purnama, Wikal; Sulaeman Hariri, Zidan; Firda Silvia, Vivi; Haliza Dewi, Nur; Ramaniya Maharani, Syahla; Nur Aulya, Fasya; Hawanun Azzahra, Adilla; Amalina Putri Nugraha, Razita; Femilia, Dela; Amalia, Reva; Dwi Hanafian, Maulana; Alya Nurfauziah, Zahwa; Prastika, Nida; Mulyadi, Adi; Azzahra, Nazwa; Putra Pratama, Akmal; Pangestu, Andhika; Syahran Mawarid Taslim, Muhammad; Apriyani, Mutia; Noer Aprilyani, Suci; Mulyani, Eva
Catimore: Jurnal Pengabdian Kepada Masyarakat Vol 5 No 1 (2026): Catimore: Jurnal Pengabdian kepada Masyarakat
Publisher : LSM Catimore dan Sahabat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56921/cpkm.v5i1.360

Abstract

Ciampanan Village has abundant local papaya resources; however, their utilization remains limited as papaya is mostly sold as fresh fruit while the seeds are discarded as waste. This community service program aimed to enhance the added value of papaya through innovation in processing papaya seeds into herbal tea and papaya fruit into jam. The implementation method involved participatory approaches through observation, hands-on training, and community mentoring. The results showed an increase in community knowledge and skills in processing local food products. Participants were able to produce papaya jam and papaya seed tea that are feasible for consumption and have potential to be developed as household-scale businesses. This program demonstrates that optimizing local agricultural resources can support economic empowerment and sustainable rural development.
Co-Authors Alya Nurfauziah, Zahwa Amalia, Reva Amalina Putri Nugraha, Razita Apriyani, Mutia Asicha, Nur Azzahra, Nazwa Dwi Hanafian, Maulana Femilia, Dela Firda Silvia, Vivi Haliza Dewi, Nur Hawanun Azzahra, Adilla Mulyadi, Adi Mulyani, Eva Noer Aprilyani, Suci Nur Aulya, Fasya Prastika, Nida Purnama, Wikal Putra Pratama, Akmal Rahmat Cahyanur Ramaniya Maharani, Syahla Resultanti, Resultanti Sulaeman Hariri, Zidan Syahran Mawarid Taslim, Muhammad