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All Journal Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Jurnal Penyakit Dalam Indonesia
Resultanti, Resultanti
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Biochemistry, Genetics & Molecular Biology Education Health Professions Medicine & Pharmacology Public Health

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Journal : Jurnal Penyakit Dalam Indonesia

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Efektivitas dan Keamanan Beraprost untuk Pengobatan Klaudikasio Intermiten pada Critical Limb Threatening Ischemia (CLTI) Pangestu, Andhika; Asicha, Nur; Cahyanur, Rahmat; Resultanti, Resultanti
Jurnal Penyakit Dalam Indonesia Vol. 10, No. 2
Publisher : UI Scholars Hub

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Abstract

Critical limb threatening ischemia (CLTI) is the most advanced stage of peripheral arterial diseases. Alternative treatment for claudication in CLTI patients is beraprost. We aim to review effectiveness and safety beraprost for relieve symptoms in CLTI. We conducted systematic literature searching using PubMed/MEDLINE, Embase, ProQuest, and Cochrane databases. Selected articles were examined for duplication and screened by abstract and title. Then, we appraised the articles based on the critical appraisal sheet from Centre for Evidence-Based Medicine (CEBM) University of Oxford. We found one systematic review-meta analysis (SR-MA) which involved 4,477 randomized participants. The results from this study are moderate quality evidence that prostanoids reduced rest pain (RR 1.30; 95%CI 1.06 – 1.59) and promoted ulcer healing (RR 1.24; 95%CI 1.04 – 1.48). In adult patients with CLTI and intermittent claudication as the primary complaint, vasodilator agents such as beraprost have a beneficial effect and a favorable therapeutic response. Numerous effects, including cardiovascular benefit, adverse events, resting pain relief, ulcer healing, outcome maximum walking distance (MWD), and pain-free walking distance, demonstrate the benefit (PFWD). The benefits of beraprost differ depending on the mechanism of action and pharmacokinetics of the drugs.
Abses Iliopsoas Akibat Tuberkulosis: Sebuah Laporan Kasus Sari, Desty Gusti; Imanuela, Rosatya; Resultanti, Resultanti
Jurnal Penyakit Dalam Indonesia
Publisher : UI Scholars Hub

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Psoas abscess is a rare condition with an unclear clinical presentation where there is a collection of pus in the iliopsoas compartment. The most common cause of an iliopsoas abscess is infection with Staphylococcus aureus. Mycobacterium tuberculosis rarely causes psoas abscesses, with an incidence of about 10–30% of extrapulmonary tuberculosis and only 3% of tuberculosis in general. Psoas abscesses due to tuberculosis is quite rare and has non-specific symptoms, so it sometimes causes a late diagnosis. This case study reports on male aged 43-year-old patient who had previously been diagnosed with spondylitis tuberculosis (TBC) and complained of pain accompanied by swelling in both legs and scrotum. A diagnostic examination was performed. Computed tomography (CT) scan abdomen contrast found an abscess on the iliopsoas, so the patient was treated with anti-TBC drugs and percutaneous drainage for abscess evacuation. Clinical and laboratory improvements were obtained after the therapeutic action was carried out.
Co-Authors Asicha, Nur Imanuela, Rosatya Johan, Kenneth Pangestu, Andhika Rahmat Cahyanur Sari, Desty Gusti