Yahya Nurlianto
Obstetric and Gynaecology Consultant, dr. M. Salamun Air Force Hospital, Indonesia

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A Thorough Systematic Review of The Impact of Educational Interventions On The Quality of Life For Pregnant Women Experiencing Nausea And Vomiting Mutia Juliana; Yahya Nurlianto
The Indonesian Journal of General Medicine Vol. 1 No. 6 (2024): The Indonesian Journal of General Medicine
Publisher : International Medical Journal Corp. Ltd

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Background: Hyperemesis gravidarum (HG) is the primary cause of early pregnancy hospitalization and sick leave, causing significant financial costs. Improper management can result in negative pregnancy outcomes and lower women's quality of life. Methods: The systematic review included research articles assessing the impact of educational intervention on women with NVP's quality of life, published from 2000 to 2023. Result: The review explores the impact of educational interventions on the quality of life of pregnant women in Iran, Taiwan, Norway, and the UK. The studies, conducted in hospitals, health centers, and social media, measured QOL using tools like NVPQOL, SF36.v2, EQ-5D, and QoLS. Five of the seven RCT studies reported a significant effect. Conclusion: The study explores the impact of educational interventions on pregnant women experiencing nausea and vomiting related-pregnancy (NVP) and their quality of life. It found that exercise education and strong support networks can improve QOL. However, factors like pain, depression, low education, younger age, and lack of a partner can negatively affect QOL.
An Evaluation Of Prophylactic Tranexamic Acid's Ability To Stop Postpartum Hemorrhage: A Systematic Review Mutia Juliana; Yahya Nurlianto
The Indonesian Journal of General Medicine Vol. 1 No. 6 (2024): The Indonesian Journal of General Medicine
Publisher : International Medical Journal Corp. Ltd

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Abstract

Background: Tranexamic acid (TXA) has been used to treat acute bleeding in trauma-related settings, with low side effects. However, the benefits of prophylactic TXA use remain unclear, raising the possibility of administration before PPH diagnosis. Methods: The study followed the PRISMA 2020 guidelines and developed a systematic review and meta-analysis of blinded and randomized clinical trials to determine the impact of prophylactic TXA use on bleeding volume in cesarean or vaginal deliveries, focusing on English studies. Result: TXA showed significant effects on post-partum bleeding reduction, with lower hemoglobin variation compared to the control group. However, some studies reported mild side effects and the effect was even greater in cesarean delivery. Risk factors for bleeding were considered. Conclusion: Promising outcomes have been observed in lowering blood component requirements and preventing postpartum hemorrhage (PPH) with TXA, a prophylactic treatment for PPH. Even though the use of uterotonics was reduced, a recent multicenter RCT conducted in France was unable to demonstrate a meaningful decline in PPH diagnoses. The study also showed a great deal of variability in TXA use and how it affected cesarean deliveries.