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All Journal The Indonesian Journal of General Medicine
Mutia Juliana
Faculty of Midwifery, General Achmad Yani University, Bandung, Indonesia
Dentistry Health Professions Medicine & Pharmacology Public Health Veterinary

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The Impact Of Vitamin D Supplementation During Pregnancy On Preeclampsia Risk: A Comprehensive Systematic Review Mutia Juliana
The Indonesian Journal of General Medicine Vol. 1 No. 8 (2024): The Indonesian Journal of General Medicine
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/rz6zh532

Abstract

Background: Studies suggest vitamin D's potential role in reducing early-onset preeclampsia risk through improved endothelial function and reduced oxidative stress. This systematic review aims to evaluate the impact of vitamin D supplementation on the risk of preeclampsia based on literatures of the last 10 years. Methods: The review adhered to PRISMA 2020 standards and analyzed full-text English literature from 2014 to 2024. It excluded editorials, review papers from the same journal, and submissions lacking a DOI. Literature sources included PubMed, SagePub, SpringerLink, and Google Scholar. Result: A total of  500 articles were retrieved from online databases (PubMed, SagePub, SpringerLink and Google Scholar). After three rounds of screening, five articles directly relevant to the systematic review were selected for full-text reading and analysis. Conclusion: Vitamin D plays a crucial role in various physiological processes, including calcium homeostasis, immune modulation, and vascular function, all of which are implicated in the pathogenesis of preeclampsia.
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