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Institut Teknologi Sepuluh Nopember
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THE ADVANCED ELECTRIC FIELD FROM QUAD-ELECTRODE MODE FOR BLOOD CANCER TRAPPING: SIMULATION STUDY M. Firdhaus; U. Farahdina; V. Z Zulfa; M. Haekal; Endarko; A. Rubiyanto; Nasori; A. R. H. Tahier; Darsono
Jurnal Sains Materi Indonesia Vol. 23 No. 2 (2022)
Publisher : BRIN Publishing (Penerbit BRIN)

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

THE ADVANCED ELECTRIC FIELD FROM QUAD-ELECTRODE MODE FOR BLOOD CANCER TRAPPING: SIMULATION STUDY. Blood cancer is a disease caused by the rapid cleavage of white blood cells (WBC), which increases in the human circulatory system. Furthermore, based on the original nature of WBC during cleavage, which is the same as ionic bonds, electric field filtering, and trapping is used to treat leukemia patients. The electric field generated by the electrode with an AC voltage source plays a role in the migration of the WBC to high electric field intensity. The Quad-electrode field distribution is conducted using the Finite Element Method (FEM), and an electric field gradient analysis is conducted to determine the effectiveness of each coordinate system. According to the simulation results, the second model with an input voltage of 0.68 V has the highest intensity of electric field distribution, with an effective depth at Z = 30 mm, and the best coordinate along the X-axis and Y-axis are 30 mm. In conclusion, the center of the Quad-electrode system center is the best location for placing filters and trapping leukocytes by utilizing electric field distribution on the electrode system for the development of blood cancer biomedical therapy technology.
The Influence of Multi-frequency Current Injection in Image Reconstruction for Two-Dimensional High-Speed Electrical Impedance Tomography (EIT) Aris Widodo; Agus Rubiyanto; Endarko
IPTEK The Journal of Engineering Vol. 5 No. 1 (2019)
Publisher : Institut Teknologi Sepuluh Nopember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12962/joe.v5i1.5019

Abstract

The image reconstruction for two-dimensional high-speed Electrical Impedance Tomography (EIT) has been successfully studied with multi-frequency current injection. The aim of this study is to get the best image reconstruction under the influence of multi-frequency current injection of this EIT system. In this method, we used current injection at 1 mA with varies of frequency in the range 10 to 50 kHz injected at the practical phantoms with 16 electrodes. Polyvinyl chloride (PVC) cylinder was put in the practical phantom as the anomaly. Then, The boundary voltage of the practical phantom was measured by the voltage measurement circuit. After that, it processed in the computer with Gauss-Newton Algorithm to got image reconstruction. The result showed that the best image reconstruction was achieved at 10 kHz of frequency current injection. The best image reconstruction had more accuracy of shape, position and electrical properties of an anomaly in boundary phantom than another image reconstruction result.
THE ADVANCED ELECTRIC FIELD FROM QUAD-ELECTRODE MODE FOR BLOOD CANCER TRAPPING: SIMULATION STUDY M. Firdhaus; U. Farahdina; V. Z Zulfa; M. Haekal; Endarko; A. Rubiyanto; Nasori; A. R. H. Tahier; Darsono
Jurnal Sains Materi Indonesia Vol. 23 No. 2 (2022)
Publisher : BRIN Publishing (Penerbit BRIN)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17146/jsmi.2022.23.5.6427

Abstract

THE ADVANCED ELECTRIC FIELD FROM QUAD-ELECTRODE MODE FOR BLOOD CANCER TRAPPING: SIMULATION STUDY. Blood cancer is a disease caused by the rapid cleavage of white blood cells (WBC), which increases in the human circulatory system. Furthermore, based on the original nature of WBC during cleavage, which is the same as ionic bonds, electric field filtering, and trapping is used to treat leukemia patients. The electric field generated by the electrode with an AC voltage source plays a role in the migration of the WBC to high electric field intensity. The Quad-electrode field distribution is conducted using the Finite Element Method (FEM), and an electric field gradient analysis is conducted to determine the effectiveness of each coordinate system. According to the simulation results, the second model with an input voltage of 0.68 V has the highest intensity of electric field distribution, with an effective depth at Z = 30 mm, and the best coordinate along the X-axis and Y-axis are 30 mm. In conclusion, the center of the Quad-electrode system center is the best location for placing filters and trapping leukocytes by utilizing electric field distribution on the electrode system for the development of blood cancer biomedical therapy technology.
Co-Authors A. R. H. Tahier A. Rubiyanto Agus Rubiyanto Aris Widodo Darsono M. Firdhaus M. Haekal Nasori U. Farahdina V. Z Zulfa