Rahmi Rahmi
Faculty of Medicine, Universitas Sumatera Utara

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Molecular Review: Effects of Physical Exercise in Skeletal Muscle Glucose Uptake Rahmi Rahmi
Sumatera Medical Journal Vol. 4 No. 1 (2021): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v4i1.4785

Abstract

Muscle contraction requires glucose as its main fuel. Glucose enters the muscle cells through diffusion facilitated by GLUT4. GLUT4 must be translocated from intracellular to the plasma membrane and T tubules during muscle contraction. This literature review will discuss how physical exercise can signal GLUT4 translocation for glucose uptake. Molecular signals induced by physical exercise are very complex and involve various molecules, one of which is AMPK and intracellular Ca concentration.