Article Per Year (5 Year)
p-Index From 2020 - 2025
0
P-Index
This Author published in this journals
All Journal Jurnal Ilmiah Kesehatan Keperawatan
budi ekanto
Unknown Affiliation
Health Professions Nursing Public Health

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
PERUBAHAN DISFUNGSI ENDOTEL AORTA PADA TIKUS GALUR PUTIH REMAJA YANG TERPAPAR ALCOHOL TERHADAP PEMBERIAN CURCUMIN. puguh widiyanto; budi ekanto
Jurnal Ilmiah Kesehatan Keperawatan Vol 6, No 2 (2010): JURNAL ILMIAH KESEHATAN KEPERAWATAN
Publisher : LPPM UNIVERSITAS MUHAMMADIYAH GOMBONG

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The human body has the ability to prevent and correct endothelial dysfunction by producing antioxidants. This primary antioxidant will help prevent oxidation caused by free radicals, so the blood vessels endothelial dysfunction and will not experience does not occur in atherosclerotic arteries. Under these circumstances, where the number of free radicals in the blood is very excessive, an antioxidant that is produced by the body no longer effective, so that the necessary antioxidants from the outside (secondary). This research experiments, using post test only control group design. Statistical analysis is used for the T test, to assess the effect of antioxidants (curcumin). From the results of this study proves that there is a positive influence, that curcumin can prevent endothelial cell dysfunction with no incidence of characteristics of foam cells in the aorta of male teenagers who typhoid chronic alcohol exposure. Suggestion is to increase the consumption antiokidan (curcumin) to improve vascular endothelial damage (sclerosis).   Keywords : Exposure to alcohol, the aortic endothelial dysfunction, provision of curcumin
PENGARUH PEMBERIAN TEH ROSELLA (HIBISCUS SABDARIFFA) TERHADAP KADAR SUPEROXIDE DISMUTASE (ANTIOKSIDAN TUBUH UTAMA) PADA TIKUS JANTAN REMAJA YANG DIBERI ALKOHOL Budi ekanto; Syamsudin -; tulus Puji Hastuti
Jurnal Ilmiah Kesehatan Keperawatan Vol 8, No 1 (2012): JURNAL ILMIAH KESEHATAN KEPERAWATAN
Publisher : LPPM UNIVERSITAS MUHAMMADIYAH GOMBONG

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Increase systolic blood pressure that related with impairedvasodilatation of the arterioles is affected by the decrease of NO level andincrease peroxynitrite. Nitric oxide level may be reduced by increase ofSuperoxide production that due to alcohol consumption. Superoxidedismutase activity will be decreased by its role in preventing reaction ofSuperoxide with NO to form peroxynitrite. Superoxide is reduced by SODto form hydrogen peroxide and oxygen. Oxidative stress due to alcoholconsumption lead to lower NO level and SOD activity in the blood. Theaims of this study are to examine the influence of rosela tea to the SODlevels in blood serum in rats given doses of alcohol 30 % 3 g / kg bodyweight / day.Thirty male of Wistar rats with weight 150 grams were divided intofive groups, each group consists of 6 animals. Group A was controlgroup. Group B was given by alcohol. Group C, D, E were given byalcohol and rosela. Doses 0.75 gram of dried rosela that diluted by 200cc of water gave to group C, while group D was given by rosela dose 1.5grams and 3 grams to E group. Providing alcohol and rosela conductedover 28 days by orally (orogastric tube). Rosela was given at 08.00 amand alcohol at 10:00 am. SOD levels in blood are measured aftertreatment. Results showed that Superoxide dismutase levels of groupthat were given by alcohol and 0.75 g, 1.5 g, 3 g rosela higher than thosein group that received only alcohol and control. Conclussion, rats thatwere given by rosela tea and alcohol have higher SOD level compared tocontrol group.Keywords : alcohol, rosela, Nitric oxide, SOD
Co-Authors Puguh Widiyanto Syamsudin - Tulus Puji Hastuti