Lukman Lukman
Program Studi Matematika, Fakultas Pendidikan Matematika dan Ilmu Pengetahuan, Universitas Pendidikan Indonesia, Indonesia

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LOG-RANK TEST SEBAGAI LANJUTAN DARI METODE KAPLAN-MEIER DALAM ANALISIS SURVIVAL MENGGUNAKAN BAHASA R (Studi Kasus: Treatment D-penicillamine terhadap Peluang Tahan Hidup Pasien Primary Biliary Cirrhosis (PBC) di Mayo Clinic) Ferennia Putri; BAP Martadiputra; Lukman Lukman
Jurnal Matematika, Statistika dan Komputasi Vol. 21 No. 1 (2024): SEPTEMBER 2024
Publisher : Department of Mathematics, Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/j.v21i1.36073

Abstract

From 1974 to 1984, Mayo Clinic conducted a D-penicillamine trial to improve the chances of survival of PBC patients. Mayo Clinic conducted a randomized placebo-controlled trial on patients to compare D-penicillamine with D-penicillamine. Mayo Clinic considered other variables besides the time of death or censored time in its study, namely the variables of Ascites, Hepatomegaly, Spider or the presence of esophageal varices, and other PBC symptom variables. Therefore, the author conducted this study to find out D-penicillamine as a drug treatment for PBC by only looking at the variable of time of death or censored time and the variable of drug treatment received by patients during the ten-year data collection period and completing the study with statistical science. Based on that, the author used survival analysis with the Kaplan-Meier and Log-Rank methods to find D-penicillamine as a PBC drug treatment. This study shows how to complete the analysis using the R language. The study results showed that D-penicillamine treatment was not good enough to increase the survival chances of PBC patients