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All Journal Interdental Jurnal Kedokteran Gigi (IJKG) MDJ (Makassar Dental Journal)
I Gusti Ngurah Putra Dermawan
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Biochemistry, Genetics & Molecular Biology Dentistry Medicine & Pharmacology Public Health

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IDENTIFICATION AND TREATMENT OF ERYTHEMA MULTIFORME INDUCED BY ALLOPURINOL I Nyoman Gede Juwita Putra; Raziv Ganesha; I Gusti Ngurah Putra Dermawan
Interdental Jurnal Kedokteran Gigi (IJKG) Vol. 19 No. 2 (2023): Interdental Jurnal Kedokteran Gigi (IJKG)
Publisher : Fakultas Kedokteran Gigi, Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46862/interdental.v19i2.7664

Abstract

Introduction: Allopurinol is a xanthine oxidase inhibitor and has become established as the drug of choice for preventing and treating chronic gout. Erythema multiforme (EM) is an immune-mediated reaction that involves the skin and sometimes the mucosa. Many cases of EM are caused by drugs, one of which is allopurinol. The purpose of the case study is to explain the identification of allopurinol as a predisposing factor for EM and how it is treated. Case. A 56-year-old woman came with complaints of scabs on her lips for 1 week ago, and had been treated with corticosteroid ointment for 3 days. Extraoral examination showed hemorrhagic crusts on the upper and lower lips with erosive surrounded by erythematous margins. On the extremity found a target lesion on the right hand. Based on the examination, the patient was diagnosed with Erythema Multiforme with a differential diagnosis of herpes labialis and herpes associated erythema multiforme. Case Management. The therapy in this case was giving antihistamines for 1 week, NaCl 0.9% compresses on the lips for 30 minutes 3 times a day, after 2 weeks of treatment added with the application of 1% hydrocortisone cream as an anti-inflammatory and petroleum jelly on the lips as a moisturizer. Conclusion. Identification of the etiology of this EM case was carried out through anamnesis and history of drugs consumed as well as administration of topical corticosteroids as anti-inflammatories and oral antihistamines to reduce allergic reactions.
The effect of using swamp water for daily needs on the saliva pH of non-smoking male farmers in Senajam Village, West Kalimantan Province: Pengaruh penggunaan air rawa sebagai kebutuhan keseharian terhadap pH saliva petani laki-laki non perokok di Dusun Senajam Provinsi Kalimantan Barat Raziv Ganesha; I Gusti Ngurah Putra Dermawan; Intan Kemala Dewi; Agustina Ursula Dayuta
Makassar Dental Journal Vol. 14 No. 3 (2025): Volume 14 Issue 3 December 2025
Publisher : Makassar Dental Journal PDGI Makassar

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Abstract

Dengan pH yang seimbang, saliva melindungi permukaan gigi dari kerusakan, menghambat perkembangan bakteri patogen, serta mendukung proses remineralisasi alami pada email gigi. Kualitas air yang digunakan sehari-hari memainkan peran penting dalam kesehatan tubuh, termasuk kesehatan gigi dan mulut. Berbagai jenis air memiliki karakteristik unik, termasuk pH atau tingkat keasamannya, yang dapat berdampak pada kesehatan mulut dan jaringan di sekitarnya. Penelitian ini bertujuan untuk memberikan wawasan lebih lanjut mengenai kondisi pH saliva pada individu non-perokok, khususnya pada komunitas petani laki-laki di Dusun Senajam yang menggunakan air rawa sebagai kebutuhan keseharian sehingga mengungkap pengaruh antara kebiasaan penggunaan air rawa yang berkonsentrasi asam terhadap kondisi kesehatan rongga mulut. Hasil menunjukkan 58% peserta penelitian menunjukkan nilai asam, 10,5% menunjukkan nilai basa dan 31,5% menunjukkan nilai normal. Disimpulkan bahwa penggunaan air rawa yang bersifat asam dalam jangka panjang berkontribusi pada penurunan pH saliva.
Co-Authors Agustina Ursula Dayuta I Nyoman Gede Juwita Putra Intan Kemala Dewi Raziv Ganesha