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Salsabila Andiyanti Putri
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Kajian Efektivitas, Toksisitas, dan Cost-Effectiveness Obat-Obatan Penyakit Alzheimer Salsabila Andiyanti Putri; Anggadiredja, Kusnandar
Acta Pharmaceutica Indonesia Vol. 48 No. 1 (2023)
Publisher : School of Pharmacy Institut Teknologi Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/api.v48i1.22224

Abstract

Alzheimer is a neurological disease characterized by loss of cognitive and non-cognitive functions. Drugs that can be used to treat Alzheimer’s disease include donepezil, galantamine, rivastigmine, and memantine. This literature review covers the effectiveness, toxicity, and cost-effectiveness of these four drugs as Alzheimer's therapy options. Review of the pertinent literatures from the databases Google Scholar, Pubmed, and Science Direct showed that galantamine has the best effectiveness compared to other drugs because it can improve all aspects of Alzheimer’s disease. The four drugs do not have a fixed toxic dose, but the effects they cause are not much different from one drug to another. Donepezil, galantamine, and memantine were cost-effective, whereas rivastigmine was not. Key words: Alzheimer’s disease, Alzheimer's drugs
Co-Authors Kusnandar Anggadiredja