ABSTRACT Construction is a difficult, primarily land-based activity in which workers face a multitude of hazards, some of which go unrecognized. It is well-known for being one of the most dangerous industries in the world. It is labor-demanding and necessitates a great deal of movement of materials and machines within a tight space, resulting in a high level of safety concerns. This study aims to investigate the safety performance on Ghanaian construction sites in terms of the problems causing accidents on sites and how to curb them, if not fully eradicated. The objective of this research is to investigate the safety indicators and barriers to safety performance on Ghanaian construction sites and also identify strategies to improve safety performance on Ghanaian construction sites. The quantitative approach was adopted for this study, and questionnaires were distributed in the Kumasi metropolis with the use of the snowball sampling technique. The data received from the surveys was coded and examined utilising version 20 of the Statistical Package for Social Sciences (SPSS) and Microsoft Excel. "Data interpretation" refers to the process of explaining the meaning of pie charted data. Graphed data, the RII, and One Sample T tests were applied during the analysis. The findings suggested ten indicators for measuring safety performance, ten barriers that hinders the implementation of safety performance and eight strategies to help improve upon the safety performance in the Ghanaian construction industry. The findings confirmed that all the indicators, barriers and strategies are vital and need to be acted on. Examples of the safety indicators include; creation of safety policy, provision of a secure workplace environment, implementation of safety management system. Examples of the barriers that hinders safety performance include; low or insufficient resources, level of qualified personnel, lack of inspection on the effectiveness of safety performance on site by an appropriate government agencies or authority. Examples of the strategies that would improve upon safety performance include; effective use of Personal Protective Equipment (PPE), random site visits by safety inspectorates from the OHS agencies, mandatory safety training program for workers on site by the management. This study would aid construction firms, managers, construction professionals, artisans and laborers to reduce accidents on sites, hence, increasing their productivity and success rate in cutting unnecessary accident cost and safety fines during construction if followed and implemented.