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All Journal Jurnal Indonesia Sosial Sains Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
I Ketut Suardamana
Universitas Udayana
Humanities Astronomy Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Energy Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Neuroscience Physics Public Health Social Sciences

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Descriptive Profile of Anaphylactic Reaction Patients Hospitalized at RSUP Prof. DR. I.G.N.G Ngoerah Period 2018-2023 Gede Bagus Rawida Wijaya; I Ketut Suardamana
Jurnal Indonesia Sosial Sains Vol. 5 No. 08 (2024): Jurnal Indonesia Sosial Sains
Publisher : CV. Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/jiss.v5i08.1215

Abstract

Introduction: Anaphylactic reaction is a severe, potentially life-threatening systemic hypersensitivity reaction caused by a specific allergen. This study aimed to evaluate the clinical profile of anaphylactic patients hospitalized in Prof. Dr. I.G.N.G. Ngoerah Hospital, Denpasar. Method: This was a cross-sectional descriptive study of anaphylactic patients hospitalized in our center from January 2018 to December 2023. Patients diagnosed with anaphylactic reactions were included in this study. All the data (demographic, clinical manifestations, potential trigger) were attained from medical records for descriptive analysis. Result: 292 patients were enrolled in this study; half were women (54,4%), and the median age was 38,50 years (interquartile range 24). The most common potential triggers were drugs (57%), followed by food (18,5%), blood products (14,1), insect bites, and other triggers (4,8%). Almost all patients experience skin and mucosal manifestations (99%). Anaphylactic shock occurs in only 22% of patients. Discussion: Previous studies have found similar results to our findings, and anaphylactic reaction caused by drugs was associated with a more severe reaction. The effect of estrogen hormones on more severe reactions has been reported in female mice, but human research is still limited. Conclusion: Further studies are needed to investigate the correlation between demographic characteristics or specific clinical manifestations with a severe reaction.
Descriptive Profile of Anaphylactic Reaction Patients Hospitalized at RSUP Prof. DR. I.G.N.G Ngoerah Period 2018-2023 Gede Bagus Rawida Wijaya; I Ketut Suardamana
Jurnal Indonesia Sosial Sains Vol. 5 No. 08 (2024): Jurnal Indonesia Sosial Sains
Publisher : CV. Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/jiss.v5i08.1215

Abstract

Introduction: Anaphylactic reaction is a severe, potentially life-threatening systemic hypersensitivity reaction caused by a specific allergen. This study aimed to evaluate the clinical profile of anaphylactic patients hospitalized in Prof. Dr. I.G.N.G. Ngoerah Hospital, Denpasar. Method: This was a cross-sectional descriptive study of anaphylactic patients hospitalized in our center from January 2018 to December 2023. Patients diagnosed with anaphylactic reactions were included in this study. All the data (demographic, clinical manifestations, potential trigger) were attained from medical records for descriptive analysis. Result: 292 patients were enrolled in this study; half were women (54,4%), and the median age was 38,50 years (interquartile range 24). The most common potential triggers were drugs (57%), followed by food (18,5%), blood products (14,1), insect bites, and other triggers (4,8%). Almost all patients experience skin and mucosal manifestations (99%). Anaphylactic shock occurs in only 22% of patients. Discussion: Previous studies have found similar results to our findings, and anaphylactic reaction caused by drugs was associated with a more severe reaction. The effect of estrogen hormones on more severe reactions has been reported in female mice, but human research is still limited. Conclusion: Further studies are needed to investigate the correlation between demographic characteristics or specific clinical manifestations with a severe reaction.
Hubungan Indeks Massa Tubuh dan Kadar Antibodi IgG Pasca Vaksinasi COVID-19 Andry Ganesha Rombe; I Ketut Suardamana
Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Vol. 6 No. 2 (2026): Juli: Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jikki.v6i2.10883

Abstract

Body Mass Index (BMI) is a standard measure to assess nutritional status and potential health risks. During the COVID-19 pandemic, BMI has been associated with varying disease severity and immune responses. As vaccines remain essential to pandemic control, post-vaccination IgG levels have become a key indicator of protection. However, the impact of BMI on IgG responses remains unclear, with studies showing mixed results. This study aims to evaluate the relationship between BMI and IgG antibody levels after COVID-19 vaccination. A cross-sectional study was conducted involving 76 respondents. Data collected included BMI (based on WHO classification), weight, height, history of COVID-19 infection, vaccine type, and number of doses. IgG levels were measured using immunoassay techniques. Correlations were analyzed using Spearman’s rho and Pearson tests. No significant correlation were found between BMI and IgG levels (r = -0.159; p = 0.242). Weight (r = -0.029; p = 0.833) and height (r = -0.064; p = 0.638) also showed no association with IgG levels. A weak positive correlation was observed between prior COVID-19 infection and IgG level (r = 0.231; p = 0.087), though not statistically significant. BMI, body weight, and height did not significantly influence IgG antibody levels following COVID-19 vaccination. Prior infection may have a slight effect, but rises requirements for further studies involving larger populations to clarify this potential relationship.
Co-Authors Andry Ganesha Rombe Gede Bagus Rawida Wijaya