Sinardja, Cyndiana Widia Dewi
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HUBUNGAN TEKANAN DARAH TINGGI TERHADAP KEJADIAN STROKE DI RSUP PROF. DR. I.G.N.G NGOERAH Priyatna, Rosabel Eugene; Sinardja, Cyndiana Widia Dewi; Artana, I Gusti Ngurah Bagus
E-Jurnal Medika Udayana Vol 12 No 5 (2023): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2023.V12.i05.P07

Abstract

Stroke is a condition that occurs when blood flow to the brain is cut off due to blockage or rupture of blood vessels to the brain, causing brain cell death. Stroke is a disease that has a very high level of morbidity and mortality, especially in Indonesia. Hypertension is one of the main factors of stroke. This study was aimed to determine the relationship of hypertension to the incidence of stroke in RSUP Prof. Dr. I.G.N.G Ngoerah. This study used a cross-sectional analytic observational study design on 150 stroke patients at RSUP Prof. Dr. I.G.N.G Ngoerah in the period June 2021-June 2022. This study shows the proportion of non-hemorrhagic stroke is 56.7% and hemorrhagic stroke is 43.3%; stroke patients who have hypertension by 72.7%; stroke was more common in patients aged ?58 years with a proportion of 52%; and stroke was more common in male patients with a proportion of 63.3%. For the non-parametric correlation value of hypertension with non-hemorrhagic stroke and hemorrhagic stroke found r = 0.265 with p value = 0.001; p<0.05. This value indicates a weak positive relationship between hypertension to the incidence of non-hemorrhagic stroke and hemorrhagic stroke which proved significant. This is due to hypertension causing endothelial dysfunction so that it can trigger the formation of arterosclerosis and/or rupture of blood vessels. Preventive measures to maintain blood pressure play an important role in preventing complications of stroke.
An overview of treatment for atrial septal defect with pulmonary hypertension Gudi, Veronika Anjelina Aho; Suastika, Luh Oliva Saraswati; Sinardja, Cyndiana Widia Dewi
Malahayati International Journal of Nursing and Health Science Vol 6, No 7 (2024)
Publisher : Program Studi Ilmu Keperawata Fakultas Kedokteran Universitas Malahayati Bandar Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/minh.v6i7.13212

Abstract

Background: Atrial Septal Defect (ASD) is a congenital heart defect which can be the cause of comorbidities in the form of Pulmonary Arterial Hypertension (PAH) and therapy cannot be done simply by correcting the ASD but requires further study and evaluation.Purpose: Describe the treatment given to patients with ASD and PAH and the correlation between the administration of interventional therapy and the patient's probability of PH.Method: This study is a descriptive quantitative using a cross-sectional research design. The sampling technique was total sampling method. The samples were 41 ASD patients with PAH at Prof. Ngoerah General Hospital in Denpasar in 2022. Patients under 18 years of age and those with other congenital heart disease will be excluded. The demographic characteristics assessed were the patient's age and gender. The therapy data included information on medical therapy and intervention therapy.Results: Focus of medical therapy was supportive therapy rather than specific PAH therapy. Percutaneous ASD closure was the most widely-used intervention therapy compared to surgical ASD closure. Based on statistical analysis, the p value > 0.05 is 0.284, so there is no significant correlation between the probability of the patient's pH and the provision of intervention therapy.Conclusion: At Prof Ngoerah General Hospital Denpasar, the majority of ASD patients with complications of pulmonary hypertension were females aged between 21 to 30 years. The medical therapy given is adjusted based on the severity of PH as assessed through echocardiography examination. Majority of patients received supportive therapy compared to specific therapy for PAH. Medical therapy is prioritized for patients who have contraindication criteria for interventional therapy. Percutaneous ASD Closure was found to be the largest percentage in interventional therapy regardless of the severity, except for patients who were indicated to undergo surgical ASD closure. There is no significant relationship between the patient's PH probability level and the choice of intervention therapy.