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All Journal Bioscientia Medicina : Journal of Biomedicine and Translational Research Bioscientia Medicina : Journal of Biomedicine and Translational Research
Kiki Ahmad Rizki
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Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Neuroscience

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Primary Malignant Melanoma of the Hard Palate: A Rare Case Report Putri, Syifa Azizah; Kiki Ahmad Rizki
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 11 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i11.1117

Abstract

Background: Primary malignant melanoma of the oral cavity is an uncommon and aggressive malignancy with a poor prognosis. The hard palate is a rare site for primary melanoma, and early diagnosis is often challenging due to its asymptomatic nature in the initial stages. Case presentation: We present the case of a 58-year-old female who presented with a pigmented lesion on the right hard palate and a neck mass. The lesion had been present for a year and had gradually increased in size. The neck mass had appeared three months prior and was associated with pain. Imaging and biopsy confirmed the diagnosis of malignant melanoma with cervical lymph node metastasis. The patient underwent wide excision with right hemimaxillectomy and modified radical neck dissection type II, followed by planned postoperative radiation therapy. Conclusion: This case highlights the importance of considering melanoma in the differential diagnosis of pigmented oral lesions. Early diagnosis and aggressive treatment are crucial for improving outcomes in this rare but aggressive malignancy. The use of adjuvant therapies, such as radiation and targeted therapy, may be beneficial in select cases.
Analysis of Risk Factors for Psychological Stress in Breast Cancer Patients: Observational Study in West Java, Indonesia Pancakarsa, Eka Prasetya; Monty P. Soemitro; Arief Budianto; Maman Abdurahman; Kiki Ahmad Rizki; Yohana Azhar; Dodi L. H. L. Gaol
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 7 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i7.1037

Abstract

Background: Breast cancer is one of the most common types of cancer in women in Indonesia. Diagnosis and treatment of breast cancer can cause significant psychological stress in the sufferer. This study aims to analyze the risk factors for psychological stress in breast cancer sufferers in West Java, Indonesia using an observational study with multivariate analysis. Methods: This research involved 200 breast cancer sufferers recruited from hospitals in West Java. Data was collected using a questionnaire that measured psychological stress, demographic factors, social factors, and medical factors. Data analysis was carried out using multinomial logistic regression to identify risk factors associated with the occurrence of psychological stress. Results: The research results show that the incidence of psychological stress in breast cancer sufferers in West Java is 42%. Risk factors that are significantly associated with the occurrence of psychological stress are young age, unmarried marital status, low social support, high levels of anxiety, and advanced cancer stage. Conclusion: This research shows that several risk factors can increase the incidence of psychological stress in breast cancer sufferers in West Java. These findings can be used to develop more effective interventions to help breast cancer survivors cope with psychological stress.
Extramammary Paget's Disease of the Vulva: A Rare Case Report Pancakarsa, Eka Prasetya; Kiki Ahmad Rizki; Monty P. Soemitro; Maman Abdurahman; Yohana Azhar; Dodi L. H. L. Gaol
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 7 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i7.1039

Abstract

Background: Extramammary Paget’s Disease (EMPD) is a rare disease characterized by intraepithelial involvement of the skin by non-squamous carcinoma cells in areas containing apocrine glands such as the vulva, perineum, perianal area, scrotum, and penis. Case presentation: A 48 year old woman complained of a non-healing wound in the genital area for 1 year. The wound feels painful and does not bleed easily. No lumps were found anywhere else. The patient works as a private employee with minimal exposure to sunlight. No history of trauma. There is a history of surgical biopsy with the result of a malignant tumor with an impression Extramammary Paget Disease. Conclusion: We present a case of a rare malignant tumor with EMPD impression of the vulva, extending to the perineum and suprapubic.
Analysis of Risk Factors for Psychological Stress in Breast Cancer Patients: Observational Study in West Java, Indonesia Pancakarsa, Eka Prasetya; Monty P. Soemitro; Arief Budianto; Maman Abdurahman; Kiki Ahmad Rizki; Yohana Azhar; Dodi L. H. L. Gaol
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 7 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i7.1037

Abstract

Background: Breast cancer is one of the most common types of cancer in women in Indonesia. Diagnosis and treatment of breast cancer can cause significant psychological stress in the sufferer. This study aims to analyze the risk factors for psychological stress in breast cancer sufferers in West Java, Indonesia using an observational study with multivariate analysis. Methods: This research involved 200 breast cancer sufferers recruited from hospitals in West Java. Data was collected using a questionnaire that measured psychological stress, demographic factors, social factors, and medical factors. Data analysis was carried out using multinomial logistic regression to identify risk factors associated with the occurrence of psychological stress. Results: The research results show that the incidence of psychological stress in breast cancer sufferers in West Java is 42%. Risk factors that are significantly associated with the occurrence of psychological stress are young age, unmarried marital status, low social support, high levels of anxiety, and advanced cancer stage. Conclusion: This research shows that several risk factors can increase the incidence of psychological stress in breast cancer sufferers in West Java. These findings can be used to develop more effective interventions to help breast cancer survivors cope with psychological stress.
Extramammary Paget's Disease of the Vulva: A Rare Case Report Pancakarsa, Eka Prasetya; Kiki Ahmad Rizki; Monty P. Soemitro; Maman Abdurahman; Yohana Azhar; Dodi L. H. L. Gaol
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 7 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i7.1039

Abstract

Background: Extramammary Paget’s Disease (EMPD) is a rare disease characterized by intraepithelial involvement of the skin by non-squamous carcinoma cells in areas containing apocrine glands such as the vulva, perineum, perianal area, scrotum, and penis. Case presentation: A 48 year old woman complained of a non-healing wound in the genital area for 1 year. The wound feels painful and does not bleed easily. No lumps were found anywhere else. The patient works as a private employee with minimal exposure to sunlight. No history of trauma. There is a history of surgical biopsy with the result of a malignant tumor with an impression Extramammary Paget Disease. Conclusion: We present a case of a rare malignant tumor with EMPD impression of the vulva, extending to the perineum and suprapubic.
Primary Malignant Melanoma of the Hard Palate: A Rare Case Report Putri, Syifa Azizah; Kiki Ahmad Rizki
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 11 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i11.1117

Abstract

Background: Primary malignant melanoma of the oral cavity is an uncommon and aggressive malignancy with a poor prognosis. The hard palate is a rare site for primary melanoma, and early diagnosis is often challenging due to its asymptomatic nature in the initial stages. Case presentation: We present the case of a 58-year-old female who presented with a pigmented lesion on the right hard palate and a neck mass. The lesion had been present for a year and had gradually increased in size. The neck mass had appeared three months prior and was associated with pain. Imaging and biopsy confirmed the diagnosis of malignant melanoma with cervical lymph node metastasis. The patient underwent wide excision with right hemimaxillectomy and modified radical neck dissection type II, followed by planned postoperative radiation therapy. Conclusion: This case highlights the importance of considering melanoma in the differential diagnosis of pigmented oral lesions. Early diagnosis and aggressive treatment are crucial for improving outcomes in this rare but aggressive malignancy. The use of adjuvant therapies, such as radiation and targeted therapy, may be beneficial in select cases.
Co-Authors Arief Budianto Dodi L. H. L. Gaol Maman Abdurahman Monty P. Soemitro Pancakarsa, Eka Prasetya Putri, Syifa Azizah Yohana Azhar