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All Journal Bioscientia Medicina : Journal of Biomedicine and Translational Research PREPOTIF : Jurnal Kesehatan Masyarakat Bioscientia Medicina : Journal of Biomedicine and Translational Research
Purwanta, Raymond Sebastian
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Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Successful Management of Complex Intestinal Tuberculosis with Ileal Perforation: A Case Report Maryella Ernestien Thioluna; Purwanta, Raymond Sebastian
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 12 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i12.1136

Abstract

Background: Intestinal tuberculosis (ITB) with ileal perforation represents a formidable challenge in the realm of extrapulmonary tuberculosis. This case report underscores the complexities inherent in managing such cases, highlighting the critical need for a multidisciplinary approach that integrates pharmacological and surgical interventions. Case presentation: A 57-year-old male presented with a history of both pulmonary and intestinal tuberculosis, complicated by ileal perforation. He had previously undergone a six-month course of anti-tuberculosis treatment and a laparotomy for ileal perforation repair. The patient's current presentation included abdominal pain, nausea, and vomiting, indicative of obstructive ileus. Diagnostic assessments revealed elevated inflammatory markers and imaging confirmed partial obstructive ileus and active pulmonary tuberculosis. The patient was managed with extended anti-tuberculosis therapy and intravenous antibiotics, resulting in significant clinical improvement and enhanced quality of life. Conclusion: This case report emphasizes the importance of early detection, comprehensive assessment, and individualized treatment plans in managing complex ITB cases. The successful outcome achieved in this case underscores the efficacy of a multidisciplinary approach that combines pharmacological and surgical interventions.
MANAGEMENT OF LEPTOSPIROSIS WITH COMPLICATIONS - CASE REPORT Massie, Eugenia Gabrielle Carey; Purwanta, Raymond Sebastian
PREPOTIF : JURNAL KESEHATAN MASYARAKAT Vol. 8 No. 2 (2024): AGUSTUS 2024
Publisher : Universitas Pahlawan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/prepotif.v8i2.32607

Abstract

Laporan kasus ini menyajikan seorang pria berusia 54 tahun dengan leptospirosis ikterik dan dugaan gangguan ginjal. Leptospira adalah bakteri penyebab leptospirosis, penyakit zoonosis yang sering terjadi selama musim banjir. Leptospirosis memiliki berbagai manifestasi klinis, dari gejala ringan seperti sakit kepala dan mialgia hingga bentuk berat yang dikenal sebagai sindrom Weil, ditandai dengan jaundice, gangguan ginjal, dan perdarahan. Indonesia memiliki insiden leptospirosis yang tinggi, menempati peringkat ketiga di dunia untuk angka kematian. Pasien, berasal dari daerah yang baru-baru ini terkena banjir, datang dengan keluhan utama demam naik-turun selama satu minggu, disertai sesak napas, ketidaknyamanan epigastrium, mual tanpa muntah, dan tinja berwarna teh. Riwayat medisnya termasuk hipertensi yang dikelola dengan amlodipine. Pemeriksaan fisik menunjukkan sklera ikterik dan tinea pedis. Tes laboratorium menunjukkan peningkatan kadar nitrogen urea darah, meskipun kreatinin serum normal, menunjukkan cedera ginjal akut yang memerlukan pemantauan lebih lanjut. Diagnosis leptospirosis didasarkan pada presentasi klinis dan riwayat paparan banjir. Pasien menerima terapi antibiotik dengan cefotaxime, serta agen gastroprotektif dan anti-inflamasi. Setelah lima hari pengobatan, ia menunjukkan perbaikan signifikan dan dipulangkan dalam kondisi stabil. Leptospirosis sering terjadi di daerah tropis dan berisiko tinggi bagi individu yang tinggal di daerah rawan banjir atau terpapar lingkungan yang mungkin terkontaminasi oleh urine tikus. Diagnosis dini dan terapi yang tepat sangat penting untuk mencegah komplikasi berat seperti gagal ginjal dan kematian. Leptospirosis adalah penyakit yang dapat dicegah dan diobati dengan diagnosis dini dan manajemen yang tepat. Perawatan medis dengan antibiotik dan perawatan suportif sangat penting untuk mencegah perkembangan penyakit yang parah.
Successful Management of Complex Intestinal Tuberculosis with Ileal Perforation: A Case Report Maryella Ernestien Thioluna; Purwanta, Raymond Sebastian
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 12 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i12.1136

Abstract

Background: Intestinal tuberculosis (ITB) with ileal perforation represents a formidable challenge in the realm of extrapulmonary tuberculosis. This case report underscores the complexities inherent in managing such cases, highlighting the critical need for a multidisciplinary approach that integrates pharmacological and surgical interventions. Case presentation: A 57-year-old male presented with a history of both pulmonary and intestinal tuberculosis, complicated by ileal perforation. He had previously undergone a six-month course of anti-tuberculosis treatment and a laparotomy for ileal perforation repair. The patient's current presentation included abdominal pain, nausea, and vomiting, indicative of obstructive ileus. Diagnostic assessments revealed elevated inflammatory markers and imaging confirmed partial obstructive ileus and active pulmonary tuberculosis. The patient was managed with extended anti-tuberculosis therapy and intravenous antibiotics, resulting in significant clinical improvement and enhanced quality of life. Conclusion: This case report emphasizes the importance of early detection, comprehensive assessment, and individualized treatment plans in managing complex ITB cases. The successful outcome achieved in this case underscores the efficacy of a multidisciplinary approach that combines pharmacological and surgical interventions.
Co-Authors Maryella Ernestien Thioluna Massie, Eugenia Gabrielle Carey