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All Journal Berkala Ilmiah Kimia Farmasi
Ariesta Yusuf Adyatama
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Biochemistry, Genetics & Molecular Biology Chemistry Medicine & Pharmacology

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Evaluation of Oral Preparations of Vitamin E as Antioxidant Using DPPH Method (Diphenyl picrylhydrazyl) Broto Anung Laksono; Nawal Ariqoh Rif'at; Tsabitah ‘Afiy Arsyah; Erlisa Alya Hanifah; Evi Wiela Astuti; Happy Rizki Rakhmawati; Clarisa Dian Cahyani; Hanun Najwa; Ariesta Yusuf Adyatama; Dena Septiyani; Zabrina Izatti Rachman; Agda Rismafuri Mukti Kirana; Achmad Toto Purnomo; Retno Sari
Berkala Ilmiah Kimia Farmasi Vol. 10 No. 1 (2023): June
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikfar.v10i1.47115

Abstract

This article aimed to evaluate the activity of Vitamin E as an antioxidant in oral pharmaceutical preparations. Vitamin E was an essential nutrient soluble in fat that had the pharmacological effect as an antioxidant. Vitamin E consisted of α, β, γ, δ-tocopherol and α, β, γ, δ-tocotrienol. The activity of Vitamin E was observed for its ability to inhibit reduction using the DPPH method. The antioxidant activity was calculated as an inhibition concentration of 50% (IC50), which was the concentration of a sample that could reduce 50% of DPPH. It was known that IC50 of Vitamin E was very strong with a value of 42,86%. Based on the article review, it could be concluded that the activity of Vitamin E as an antioxidant in oral pharmaceutical preparations was very high and strong. Keywords:  Vitamin E, Alpha-Tocopherol, Antioxidant, Activity, IC50, Oral Pharmaceutical Preparations
Co-Authors Achmad Toto Purnomo Agda Rismafuri Mukti Kirana Broto Anung Laksono Clarisa Dian Cahyani Dena Septiyani Erlisa Alya Hanifah Evi Wiela Astuti Hanun Najwa Happy Rizki Rakhmawati Nawal Ariqoh Rif'at Retno Sari Tsabitah ‘Afiy Arsyah Zabrina Izatti Rachman