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All Journal BERNAS: Jurnal Pengabdian Kepada Masyarakat Jurnal Manajemen, Akuntansi, Ekonomi Journal of Artificial Intelligence and Digital Business
Sopyan , Iyan
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PERAN PEMERINTAH DESA DALAM MENINGKATKAN PERKEMBANGAN UMKM MASYARAKAT DESA GEDE PANGRANGO KECAMATAN KADUDAMPIT KABUPATEN SUKABUMI Rosmiati, Neni; Sopyan , Iyan
Jurnal Manajemen, Akuntansi, Ekonomi Vol. 2 No. 3 (2024): Jurnal Manajemen, Akuntansi, Ekonomi
Publisher : CV. Era Digital Nusantara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59066/jmae.v2i3.618

Abstract

This study aims to analyze and describe the role played by the local government in the development of Micro, small and Medium Enterprises (MSMEs) in the area of Gede Pangrango Village, Kadudampit Disrict,Sukabumi Regency. MSMEs have an important role in the local and national economiy, as well as in creating jobs and increasing people’s income. Local governments have a significant role in providing support, regulation and facilitation for MSMEs growth. This research will analyze various policies, programs and initiatives taken by the regional government of Gede Pangrango village to support MSME development.
LITERASI DIGITAL; TINGKATKAN KAPASITAS PEMAHAMAN SISWA-SISWI SEKOLAH DI BAWAH BINAAN LP MA’ARIF MAJALENGKA Syamsul , E. Mulya; Rustandi , Enang; Gumilang Lestari, Ayu; Prayitno , Anggi; Sopyan , Iyan
BERNAS: Jurnal Pengabdian Kepada Masyarakat Vol. 6 No. 3 (2025)
Publisher : Universitas Majalengka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31949/jb.v6i3.13752

Abstract

Perkembangan zaman terus mengalami perubahan seiring dengan perkembangan teknologi, dunia teknologi telah banyak menghantarkan perubahan bagi kehidupan masyarakat di seantero dunia tak terkecuali masyarakat bangsa Indonesia, namun dalam kenyataannya perkembnagan tekonoli belum mampu di cerna oleh seluruh masyarakat Indononesia, melalui kegiatan pengabdian ini literasi digital menjadi jawaban yang kongkrit untuk membangun kesadaran masyarakat dalam dunia digital agar wujud dari digital itu menjadi penguat dalam perkembangan zaman dan peradaban yang berkelanjutan oleh karenanya melalui pengabdian masyarakat ini yang dilakukan dengan acara workshop mengambil segmen masyarakat tingkat pendidikan menengah yang terkordinir melalui guru sekolah dibawah pembinaan LP Ma’arif menjadi modal besar agar mereka dapat meliterasi ulang kepada masyarakat lainnya diluar kegiatan Pengabdian tersebut
Pre-formulations Study of Active Pharmaceutical Ingredients Amiodaron in the Development of Oral Tablet Pharmaceutical Preparations as an Anti-Arrhythmia Drug Anindya, Nisrina Raya; Fadiya, Refeyfa Najwa; Palupi, Anindya Taruni; Jannah, Aisa Zahratul; Deandrea, Helena Jessie; Sopyan , Iyan
RIGGS: Journal of Artificial Intelligence and Digital Business Vol. 4 No. 4 (2026): November - January
Publisher : Prodi Bisnis Digital Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/riggs.v4i4.5035

Abstract

Amiodaron is a broad-spectrum antiarrhythmic drug that is widely used in the management of various cardiac rhythm disorders, including ventricular and supraventricular arrhythmias. Despite its therapeutic effectiveness, Amiodaron presents complex physicochemical characteristics that pose significant challenges in the development of oral solid dosage forms, particularly tablet preparations. Therefore, a comprehensive pre-formulation study is essential to ensure the development of stable, safe, and effective pharmaceutical products. This study aims to examine the pre-formulation aspects of Amiodaron hydrochloride as a scientific basis for tablet formulation development. The research method employed was a literature-based study focusing on the physicochemical properties of Amiodaron, including ionization constants (pKa), partition coefficients (log P), solubility, dissolution behavior, polymorphism, chemical and physical stability, as well as particle and powder characteristics. Relevant data were obtained from scientific journals, pharmacopeias, and authoritative pharmaceutical references. The results indicate that Amiodaron hydrochloride is classified as a Biopharmaceutics Classification System (BCS) class II drug, characterized by low aqueous solubility and high membrane permeability. The compound is highly lipophilic, weakly basic, and sensitive to environmental factors such as light, heat, and alkaline pH conditions, which may lead to degradation. Furthermore, Amiodaron powder exhibits poor flowability and compressibility, making direct compression during tablet manufacturing difficult. Based on these findings, appropriate formulation strategies are required, including the use of inclusion complexes, hydrophilic polymers, granulation techniques, and careful selection of excipients to enhance solubility, stability, and bioavailability. This pre-formulation study is expected to provide a strong scientific foundation for the development of optimal Amiodaron tablet formulations.
Co-Authors Anindya, Nisrina Raya Deandrea, Helena Jessie Fadiya, Refeyfa Najwa Gumilang Lestari, Ayu Jannah, Aisa Zahratul Palupi, Anindya Taruni Prayitno , Anggi Rosmiati, Neni Rustandi , Enang Syamsul , E. Mulya