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Parkinson Disease Intan Sahara Zein; Khairunnisa Khairunnisa
JURNAL RISET RUMPUN ILMU KEDOKTERAN Vol. 2 No. 2 (2023): Oktober :Jurnal Riset Rumpun Ilmu Kedokteran
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrike.v2i2.1701

Abstract

Parkinson's disease is a disorder of brain function caused by the process of degeneration of the basal ganglia in the substantia nigra pars compacta (SNc) cells and is characterized by characteristics such as tremor at rest, rigidity of muscles and joints (rigidity), slowness of movement and speech (bradykinesia) and instability upright position (postural instability). Parkinson's Disease occurs in the range between the ages of 55 to 65 years and occurs in 1% -2% of people over the age of 60 years, increasing to 3.5% at the age of 85-89 years. Approximately 0.3% of the general population, the prevalence is higher in males than females with a ratio of 1.5:1.0. Manifestations that can be found in patients with Parkinson's Disease can be assessed through the Hoehn and Yahr Scale (HY). Current treatment for Parkinson's disease aims to reduce motor symptoms and slow the progression of the disease.
Seorang Pasien Laki-Laki 70 Tahun dengan Hemichorea di Rumah Sakit Daerah Cut Meutia Aceh Utara Siti Farisa; Intan Sahara Zein
Jurnal Anestesi Vol. 4 No. 1 (2026): Januari : Jurnal Anestesi: Jurnal Ilmu Kesehatan dan Kedokteran
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/anestesi.v4i1.2148

Abstract

Hemichorea is a hyperkinetic movement disorder characterized by involuntary, rapid, irregular movements affecting one side of the body. It is a rare neurological condition commonly associated with lesions of the basal ganglia, particularly the subthalamic nucleus. The etiology of hemichorea is diverse, including ischemic or hemorrhagic stroke, metabolic disturbances such as non-ketotic hyperglycemia, infections, neoplasms, and autoimmune disorders. In some cases, hemichorea may represent the initial manifestation of acute ischemic stroke, which can lead to delayed diagnosis and management due to its uncommon presentation. Diagnosis is established through careful clinical evaluation, neurological examination, laboratory investigations, and neuroimaging modalities such as computed tomography or magnetic resonance imaging. Management is mainly symptomatic and etiological, focusing on controlling the underlying cause, especially optimal glycemic control, and administering medications that reduce dopaminergic activity. The prognosis of hemichorea is generally favorable, particularly when the underlying condition is promptly identified and appropriately treated. This case highlights the importance of recognizing hemichorea as a potential manifestation of stroke and metabolic disorders to ensure timely diagnosis and effective management.