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All Journal Indonesian Journal of Chemistry Journal Midwifery Jurusan Kebidanan Politeknik Kesehatan Gorontalo
FITRIA, NURAINI
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Chemical Engineering, Chemistry & Bioengineering Chemistry Health Professions

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The Relationship Between Food Intake and The Incidence of Chronic Energy Deficiency (CED) In Pregnant-Women of Sugio Public Health Center Lamongan Fitria, Nuraini; Esyuanik, -; Pipitcahyani, Tatarini Ika; Nurwulansari, Fitria
Journal Midwifery Jurusan Kebidanan Politeknik Kesehatan Gorontalo Vol 10, No 2 (2024): Journal Midwifery
Publisher : Politeknik Kesehatan Kementrian Kesehatan Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52365/jm.v10i2.1161

Abstract

Nutrition of pregnant women must be considered, there will be problems for the mother and fetus if maternal nutrition is not provided properly. The purpose of this study was to determine whether there is a relationship between food intake and the incidence of CED in pregnant women.  The sampling method used purposive sampling. The sample of this study was 100 pregnant women. This study was conducted from August 2023 to May 2024. Spearman Rank (Rho) test was used to analyze univariate and bivariate data. The results found a correlation between energy, protein, fat, and carbohydrate intake with a p value of 0.000. This study found that food intake (protein, fat, carbohydrate, and energy) of pregnant women at the Sugio Lamongan Health Center is associated with cases of Chronic Energy Deficiency (CED). 
Co(II), Ni(II), Cu(II), and Zn(II)-(E)-N’-(2-Hydroxybenzylidene)benzohydrazide Complexes: Design, Characterization, ADME Study, and Evaluation of Antibacterial Activity Alam, Yusuf Syahril; Fitria, Nuraini; Adama, Amelia Bella Putri; Salsabilla, Shava Alifia; Duhita, Shinta Ratna; Santoso, Mardi; Martak, Fahimah
Indonesian Journal of Chemistry Vol 26, No 1 (2026)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.102090

Abstract

Four new hydrazone complexes were successfully synthesized from Co(II), Ni(II), Cu(II), and Zn(II) metal ions with the ligand (E)-N’-(2-hydroxybenzylidene)benzohydrazide. Structural elucidation was performed using CHNSO elemental analysis, FTIR, UV-vis, thermal analysis, and powder XRD. The FTIR spectra indicated the presence of coordination bonds in the form of M–N and M–O. The UV-vis spectrophotometer showed LMCT transitions. TGA characterization revealed that the Co(II), Ni(II), and Cu(II) complex compounds have an M:L ratio of 1:1, whereas the Zn(II) complex compound has an M:L ratio of 1:2. These findings were corroborated by the refinement results of the experimental and standard XRD diffractogram. Accordingly, the formulas of the Co(II), Ni(II), Cu(II), and Zn(II) hydrazone complexes are [Co(L)(Cl)(H2O)], [Ni(L)(H2O)2]Cl2, [Cu(L)(H2O)]Cl, and [Zn(L)2], respectively. Furthermore, based on the determined M:L ratios, the Co(II), Ni(II), and Cu(II) complexes are inferred to possess square planar geometries, while the Zn(II) complex is suggested to be octahedral. The ADME study, aimed at assessing their potential as drug candidates, revealed various pharmacological characteristics of the compounds. Antibacterial evaluation against Staphylococcus aureus (G+) and Escherichia coli (G−) showed the Cu(II) complex with the highest activity.
Co-Authors Adama, Amelia Bella Putri Alam, Yusuf Syahril Duhita, Shinta Ratna ESYUANIK, - Fahimah Martak Mardi Santoso Nurwulansari, Fitria Salsabilla, Shava Alifia Tatarini Pipit Ika Cahyani