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All Journal Jurnal Kedokteran Brawijaya Majalah Kesehatan FKUB
Pawestri, Aulia Rahmi
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Medicine & Pharmacology Public Health

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Promising Anthelmintic Properties of Papaya (Carica Papaya) Extract: A Literature Study An-Nisa, Syanur; Putri, Silma Amalia; Affandi, M Luqman; Pawestri, Aulia Rahmi
Jurnal Kedokteran Brawijaya Vol. 33 No. 1 (2024)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2024.033.01.8

Abstract

Helminthiasis is a lurking health issue worldwide. Currently, available anthelmintics focus on the benzimidazole group, despite their side effects and threats of anthelmintic resistance. Therefore, exploration of novel compounds with anthelmintic properties is crucial. Papaya (Carica papaya) contains active compounds with prospective anthelmintic properties. This literature review discusses the potential of papaya as an anthelmintic agent. We screened publications from indexed journals in English and Indonesian published between 2013–2023 covering topics of C. papaya active compounds and their anthelmintic properties. Seeds, leaves, bark, and stems of papaya showed various degrees of anthelmintic properties. Studies reported its efficacy against several helminth species with good safety profiles. C. papaya extract can be a promising anthelmintic candidate. Aside from its abundance, its effectiveness and safety yielded satisfactory results. Further research is needed to elicit the mechanism of C. papaya as a novel therapeutic modality for parasitic infections.
Promising Anthelmintic Properties of Papaya (Carica Papaya) Extract: A Literature Study An-Nisa, Syanur; Putri, Silma Amalia; Affandi, M Luqman; Pawestri, Aulia Rahmi
Jurnal Kedokteran Brawijaya Vol. 33 No. 1 (2024)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2024.033.01.8

Abstract

Helminthiasis is a lurking health issue worldwide. Currently, available anthelmintics focus on the benzimidazole group, despite their side effects and threats of anthelmintic resistance. Therefore, exploration of novel compounds with anthelmintic properties is crucial. Papaya (Carica papaya) contains active compounds with prospective anthelmintic properties. This literature review discusses the potential of papaya as an anthelmintic agent. We screened publications from indexed journals in English and Indonesian published between 2013–2023 covering topics of C. papaya active compounds and their anthelmintic properties. Seeds, leaves, bark, and stems of papaya showed various degrees of anthelmintic properties. Studies reported its efficacy against several helminth species with good safety profiles. C. papaya extract can be a promising anthelmintic candidate. Aside from its abundance, its effectiveness and safety yielded satisfactory results. Further research is needed to elicit the mechanism of C. papaya as a novel therapeutic modality for parasitic infections.
EXPERIENCE OF TYPE 2 DIABETES MELLITUS PATIENTS WITH NON-PHARMACOLOGICAL APPROACHES IN SUMBERSUKO VILLAGE: A QUALITATIVE STUDY Utomo, Dhamarriyo; Dewi, Putu Ayu Sintya; Akbar, Reyhan Maulana Fila; Basukresna, Damien; Njotokusumo, Kevin; Rachmi, Siti Nurluthfia; Soenarti, Sri; Pawestri, Aulia Rahmi
Majalah Kesehatan Vol. 0 No. 00 (2026): Article in Press
Publisher : Faculty of Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/

Abstract

Diabetes is a major public health concern that has a detrimental impact on health and quality of life. Prior meta-analyses have shown that non-pharmacological approaches such as physical activity, nutrition, herbal medicine, and sleep quality can effectively reduce HbA1c and fasting blood glucose levels in patients with type 2 diabetes mellitus (T2DM). Unfortunately, public awareness of these strategies remains limited, leading to poor disease control, a higher risk of complications, and increased strain on the healthcare system. This study aimed to understand the experiences and perceptions of patients with type 2 diabetes in Sumbersuko Village, Malang Regency, as they managed their condition through non-pharmacological approaches. A qualitative descriptive study was conducted in Sumbersuko Village in 2024, using purposive sampling. Ten informants in this study were patients diagnosed with T2DM, with no additional interviews conducted with family members or caregivers. Data were collected through face-to-face, in-depth, and semi-structured interviews using a phenomenological method, and then analyzed using thematic analysis. Of the ten participants, eight managed their condition by controlling their nutritional intake, four used herbal medicine, and one reported poor sleep quality. Most participants engaged in physical activity, primarily low-intensity activities such as walking, with a duration of approximately 15 to 30 minutes per session. In conclusion, the integration of nutrition, physical activity, traditional medicine, and sleep quality plays a vital role in the management and prevention of T2DM, so it is necessary to highlight a holistic treatment approach.
Co-Authors Affandi, M Luqman Akbar, Reyhan Maulana Fila An-Nisa, Syanur Basukresna, Damien Dewi, Putu Ayu Sintya Njotokusumo, Kevin Putri, Silma Amalia Rachmi, Siti Nurluthfia Sri Soenarti Utomo, Dhamarriyo