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Khoirul Haniatin
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Medicine & Pharmacology

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Journal : Eureka Herba Indonesia

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Formulation and Evaluation of Chewable Tablets from Natural Extracts: A Systematic Literature Review Nia Yuniarsih; Adam Permana; Nissa, Adinda Khoirun; Adiva Nafila Zulfa; Khoirul Haniatin; Novita Andriyani
Eureka Herba Indonesia Vol. 4 No. 3 (2023): Eureka Herba Indonesia
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/ehi.v4i3.78

Abstract

Formulation of chewable tablets from extracts of natural ingredients requires special attention in designing preparations that maintain the quality and stability of the active ingredients. The extract must have the desired pharmacological effect and be proven safe to use. This study aimed to carry out a systematic review in order to explore formulations of chewable tablets made from natural ingredients. The literature search process was carried out on various databases (PubMed, Web of Sciences, EMBASE, Cochrane Libraries, and Google Scholar) regarding the formulation and evaluation of chewable tablets from natural extracts. This study follows the preferred reporting items for systematic reviews and meta-analysis (PRISMA) recommendations. Formulation of chewable tablets from extracts of natural ingredients is an interesting approach in the development of pharmaceutical preparations. Through a selection of appropriate extracts, careful evaluation of stability, and attention to taste and aroma, these chewable tablets can provide significant benefits to patients. However, it is important to carry out careful research and testing to ensure the safety, effectiveness, and quality of these products before they are used in clinical practice.
Cambodian Simplicia (Plumeria sp.) Phytochemical Screening Study: A Systematic Literature Review Lia Fika Yuniar; Syalomita, Delika; Ismi Puji Apriani; Ira Puspawati; Zevania Toguria Nadeak; Khoirul Haniatin; Novita Andriyani; Mila Febriyanti
Eureka Herba Indonesia Vol. 4 No. 3 (2023): Eureka Herba Indonesia
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/ehi.v4i3.81

Abstract

Plumeria phytochemical screening is important to understand the chemical composition of this plant and its potential in the pharmaceutical and health fields. Through phytochemical analysis, researchers can determine the dominant compounds in plants, study their mechanism of action, and evaluate their biological activity. Phytochemical screening can be carried out using sophisticated analytical methods such as chromatography, spectroscopy, and biological assays to deeply understand the phytochemical profile of Plumeria. This study aimed to carry out a systematic review to explore the phytochemical screening of Plumeria sp. The literature search process was carried out on various databases (PubMed, Web of Sciences, EMBASE, Cochrane Libraries, and Google Scholar) regarding the evaluation of the phytochemical analysis of Plumeria sp. This study follows the preferred reporting items for systematic reviews and meta-Analysis (PRISMA) recommendations. The process of phytochemical screening was carried out qualitatively and quantitatively. Plumeria sp contains various alkaloids, flavonoids, terpenoids, and phenolic compounds.
Effectiveness of Nitrate and Beta-Blocker Drugs in Patients with Angina Pectoris: A Systematic Literature Review Maya Arfania; Adinda Khoirun Nissa; Khoirul Haniatin; Andriyani, Novita
Eureka Herba Indonesia Vol. 4 No. 3 (2023): Eureka Herba Indonesia
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/ehi.v4i3.83

Abstract

Angina pectoris is the most common clinical manifestation of myocardial ischemia and often occurs when the heart needs more blood. The main goals of treatment in patients with unstable angina are relief of symptoms, slowing disease progression, and reducing future events, especially myocardial infarction, and death. This study aimed to explore the literature regarding the effectiveness of nitrate and beta-blocker drugs in angina pectoris patients. The literature search process was carried out on various databases (PubMed, Web of Sciences, EMBASE, Cochrane Libraries, and Google Scholar) regarding risk factors and clinical overview of acute kidney injury. The search was performed using the terms: (1) "nitric oxide" OR "beta-blockers" OR "morbidity" OR "mortality" AND (2) "angina pectoris". The literature is limited to clinical studies and published in English. Sublingual nitroglycerin has become the mainstay of treatment for angina pectoris. This drug can be used to relieve acute angina or as a prophylaxis, namely before activities that can trigger angina. Beta-blockers are a type of drug that can be used to relieve angina symptoms and prevent ischemic events through the mechanism of reducing myocardial oxygen demand, reducing heart rate, and myocardial contractility. These drugs work by competitively inhibiting the action of circulating catecholamines at cell membrane beta-adrenergic receptors. In conclusion, nitrate and beta-blocker drugs are the main choices in relieving angina pectoris symptoms.
Co-Authors Adam Permana Adinda Khoirun Nissa Adiva Nafila Zulfa Ira Puspawati Ismi Puji Apriani Lia Fika Yuniar Maya Arfania Mila Febriyanti Nia Yuniarsih Nissa, Adinda Khoirun Novita Andriyani Novita Andriyani Syalomita, Delika Zevania Toguria Nadeak