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POTENSI Momordica charantia SEBAGAI ANTIDIABETIK : STUDI LITERATUR Rahma, Jaini; Munirah, Ira; Mukhlisatunnafsi, Latifah; Nur Syamsu, M.Diaz; Harahap, Herpan Syafii
Jurnal Medika Malahayati Vol 8, No 1 (2024): Volume 8 Nomor 1
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jmm.v8i1.12816

Abstract

Abstrak: Potensi Momordica Charantia Sebagai Antidiabetik : Studi Literatur. Momordica charantia (MC) atau yang dikenal dengan buah pare merupakan tanaman tradisional yang memiliki senyawa aktif seperti charantin polypeptide-P insulin untuk menurunkan kadar glukosa. Diabetes melitus adalah penyakit yang tidak menular dengan angka prevalensi penderita diabetes pada usia 20-79 tahun sekitar 11,3% yang menempatkannya di posisi ke-3 dengan wilayah arab-afrika dan pasifik barat sebagai posisi ke-1 dan ke-2. Dan Indonesia menjadi satu-satunya negara Asia Tenggara yang masuk kedalam 10 besar negara yang diproyeksikan IDF dengan angka diabetes ke-7 tertinggi. Metode yang digunakan yaitu dengan cara pencarian secara komprehensif pada 2 database (Pubmed dan Google Scholar) dari tahun 2015-2023, serta menggunakan kata kunci “Momordica charantia”, “Antidiabetes”, “Diabetes mellitus”. Data yang ditelaah dari setiap artikel penelitian yaitu meliputi identitas artikel, definisi, senyawa aktif yang berperan, patofisiologi, mekanisme kerja senyawa serta hasil dan kesimpulan penelitian. Hasil yang didapatkan menunjukkan bahwa Momordica charantia berguna untuk menurunkan glukosa darah. Ekstrak air yang terkandung dalam pare dapat mempengaruhi penggunaan glukosa dengan mengaktifkan Adenosine-monophosphate-activated protein kinase (AMPK) di jaringan otot.
Factors Related to Maternal COVID-19 Vaccination Status in Mpunda Public Health Center Warnaini, Cut; Rahma, Jaini
Jurnal Biologi Tropis Vol. 24 No. 4 (2024): Oktober - Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i4.7851

Abstract

Pregnant women were among the vulnerable population for COVID-19 infection. Therefore, it is important for pregnant women to carry out a complete COVID-19 vaccination. Complete COVID-19 vaccination status for pregnant women is when the pregnant woman has received two doses of the vaccine, where the first dose of vaccination begins in the second trimester of pregnancy and the second dose is given according to the interval of the type of vaccine. Even though the Covid-19 vaccination program has contributed to reducing death rates and infectious diseases, there will still be concerns and doubts among pregnant women and women of reproductive age. Therefore, this research is aimed to observe and analyze factors related to Maternal COVID-19 Vaccination Status specifically in Mpunda Public Health Center, Bima. This study employs a mixed-method analysis and was conducted in Mpunda Public Health Center involving 136 pregnant women. We found that socioeconomic factor such as income level, prior vaccination status, and vaccination history was significantly associated with COVID-19 vaccination status among pregnant women, but not history of adverse events. We also concluded that fear of vaccine was significantly associated with COVID-19 vaccination status among pregnant women. Results of this research hopefully can add to the growing body of evidence regarding maternal COVID-19 vaccination status and aid the policy-making process regarding this topic.