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Evaluation of Tumor necrosis factor (TNF-α) Concentration and Renal Function in the Sera of Patients with Type 2 Diabetes in Erbil City Abdulrazaaq, Zina Abdulmunem
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 7 No. 2 (2024): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v7i2.1751

Abstract

The research included a total of 70 samples, including 40 samples from patients diagnosed with type 2 diabetes and 30 samples from the control group. The participants' age ranged from 40 to 60 years. The samples were gathered during a one-year duration from the Chronic Diseases Unit / Diabetes Department in the city of Erbil. Later, blood samples were collected from both ill and healthy individuals, and then separated via the process of centrifugation. The variables that were evaluated include glucose, ferritin, Tumor necrosis factor-alpha (TNFα), CRP, urea, creatinine, and uric acid. The results of this research showed a significant rise in the concentrations of glucose, ferritin, TNF-alpha, CRP, urea, creatinine, and uric acid in persons with type II diabetes as compared to the control group.
Evaluation of β2-microglobulin, IL17, Endostatin  levels, and some biochemical variables  in patients with Chronic kidney disease  in Kirkuk city Abdulrazaaq, Zina Abdulmunem; Hameed , Nagham Imad Abdul
Academia Open Vol 10 No 1 (2025): June (In Progress)
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/acopen.10.2025.10566

Abstract

Chronic kidney disease is the most common disease in developed countries of the world and thus poses a major challenge to public health throughout the world , Method:- Samples were collected randomly from patients hospitalized in Kirkuk General Hospital, in addition to some outpatient medical clinics. 55 samples were collected for patients with chronic kidney disease CKD, whose ages were (40-75) for one year for the period (1/6/2024 to 25/10/2024) Also, 30 blood samples were collected from healthy people (as a control group) .5 ml of blood sample was collected from patients and healthy people and separated using a centrifuge to obtain the serum, after which the level of the studied variables, represented by β2-microglobulin, Interlukin-17- IL-17, Endostatin, and some biochemical variables, which included (Urea, Creatinin, Uric acid, Ferritin )Result:- This study showed a significant rise in the (Β2-MG, Endostatin, IL-17, Urea, Creatinin, Uric acid, and ferritin ) in patients with CKD compared to healthy subjects. Highlights: Chronic kidney disease challenges public health worldwide. Study analyzes β2-MG, IL-17, Endostatin, and biochemical markers in CKD patients. Results show significant biomarker elevation in CKD versus healthy subjects. Keywords: Chronic kidney disease, β2-microglobulin, IL-17, Endostatin