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All Journal Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan Jurnal Penyakit Dalam Indonesia
Gunawan, Mikhael Fabian
Unknown Affiliation
Health Professions Medicine & Pharmacology

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An Elderly Female with Pulmonary Oedema Manifestation of Dengue Hemorrhagic Fever : a Case Report Gunawan, Mikhael Fabian; Sjam, Mohammad Bhukkar Adil; Miranda, Adriana Viola
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 17 No 2 (2023): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v17i2.6552

Abstract

Dengue Hemorrhagic Fever (DHF) is an arthropod borne viral disease. The main vector of the disease are the Aedes mosquitoes. Indonesia as one of the tropical nations in South Asia falls into one of the countries in which DHF is an endemic. The notable clinical symptoms are fever usually 400c with a  biphasic pattern in 6% of DHF cases, body ache, muscles, retroorbital and joints, nausea, and vomiting. Fluid accumulation, due to plasma leakage, may occur in the abdominal cavities, pleural space, and even the lungs. The rise of non-communicable diseases like diabetes mellitus has impacted the clinical progression of DHF by increasing the risk of developing into dengue shock syndrome and atypical clinical manifestation of dengue plasma leakage and bleeding disorder. This case report discusses one of these atypical clinical manifestations of DHF. The case is an elderly female presenting in the emergency room with a DHF, Diabetes mellitus type 2, cardiomegaly, and during inpatient care developed a pulmonary Oedema.  The patient experienced prolonged fever and on the 7th day of care develops a pulmonary oedema, the patient is then moved to the intensive care unit, and with proper treatment and monitoring was able to recover from the disease
Perbandingan Ablasi Radiofrekuensi dengan Transplantasi Hati sebagai Terapi Kuratif pada Karsinoma Hepatoseluler Stadium Awal: Laporan Kasus Berbasis Bukti Gunawan, Mikhael Fabian; Safira, Ranindita Amaida; Singh, Gurmeet; Kalista, Kemal Fariz
Jurnal Penyakit Dalam Indonesia
Publisher : UI Scholars Hub

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Abstract

Hepatocellular carcinoma (HCC) is the most common type of liver cancer and the second leading cause of cancer-related mortality worldwide. Liver transplantation is considered the definitive treatment for HCC; however, in Indonesia, adult liver transplantation is still rarely performed due to donor limitations and high costs. Radiofrequency ablation (RFA) has therefore become a preferred therapeutic option in the management of HCC. This report discuss about the survival and recurrence rates of HCC in patients treated with RFA compared with those undergoing liver transplantation. A literature search was conducted using the PubMed, Cochrane, Embase, and Scopus databases. Selected articles were screened according to the predefined clinical question as well as inclusion and exclusion criteria. Critical appraisal was performed based on the 2011 Oxford Centre for Evidence-Based Medicine framework, assessing validity, importance, and applicability. Critical appraisal was conducted on two selected articles. One study reported comparable survival rates between the two groups. However, overall, both articles demonstrated that liver transplantation was associated with higher survival rates and lower recurrence rates compared with RFA. In conclusion, survival outcomes are superior with liver transplantation compared with RFA. Nevertheless, RFA may be considered in the management of hepatocellular carcinoma as a bridging therapy to liver transplantation or in situations where liver transplantation is not available.
Co-Authors Gurmeet Singh Kemal Fariz Kalista, Kemal Fariz Miranda, Adriana Viola Safira, Ranindita Amaida Sjam, Mohammad Bhukkar Adil