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All Journal Jurnal Analis Kesehatan
Redistia, P Shinta
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Health Professions Immunology & microbiology

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Perbedaan Kadar Protein Human Cpp (Copeptin) Berdasarkan Lama Menderita Pada Pasien Diabetes Melitus Redistia, P Shinta; Santosa, Budi; Kartika, Aprilia Indra
Jurnal Analis Kesehatan Vol. 12 No. 1 (2023): JURNAL ANALIS KESEHATAN
Publisher : Department of Health Analyst, Politeknik Kesehatan, Kementerian Kesehatan Tanjungkarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26630/jak.v12i1.3704

Abstract

Diabetes mellitus is a big public health problem in Indonesia. The length of time of suffering from DM is associated with a decrease in the function of pancreatic beta cells resulting in insulin resistance, which occurs in type 2 diabetes mellitus. Insulin resistance can be determined by measuring copeptin levels. The aim of this study was to determine differences in levels of human CPP protein (copeptin) in diabetes mellitus patients based on length of suffering. This type of research is observational analytic with cross sectional research design. Samples were taken from diabetes mellitus outpatients at Roemani Muhammadiyah Hospital as many as 20 samples, then the samples were examined for levels of human CPP (copeptin) protein using the ELISA (Enzyme Linked Immunosorbent Assay) method. The results showed that the average copeptin level in patients with diabetes mellitus ≤ 3 years was 1054 pg/mL and the average copeptin level in patients with diabetes mellitus > 3 years was 899 pg/mL. Statistical tests using the Independent Sample T Test obtained a significant sig value of 0.027 with a significance level of 0.05, namely 0.027 3 years, namely 899 pg/mL
Co-Authors Aprilia Indra Kartika, Aprilia Indra Budi Santosa Budi Santosa