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PATTERNS OF ANTIBIOTIC PRESCRIPTION FOR THE TREATMENT OF URINARY TRACT INFECTIONS IN KOTARAJA PUBLICAL CENTER Dehi, Rosita Irianti; Maya Permatasari; Marselino F. Paepadaseda
International Journal Of Health Science Vol. 2 No. 2 (2022): July: International Journal of Health
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/ijhs.v2i2.1418

Abstract

Urinary Tract Infection (UTI) is an infectious disease that is often found in general practice. Urinary tract infection (UTI) can be defined as the presence of bacteria in the urine where these bacteria may invade the tissues of the urinary tract. The type of research used in this research is descriptive research. This research was conducted in June 2021, in the medical records section of the Kotaraja Health Center, Jayapura City. The population in this study were all patients with UTI who were treated at the Kotaraja Publical Center in June - December 2020 with a total of 30 patients. The results showed that there were more female patients than male, namely 17 people (57%). most patients came from the age group 26-35 years as many as 11 people (37%). The most dominant type of antibiotic prescribed was ciprofloxacin in 24 patients (80%). The most dominant group of prescribed antibiotics was Fluroquinolone as many as 24 patients (80%). The most widely used dose of antibiotic preparations was Ciprofloxacin 500 mg for 24 patients (80%). The most frequent duration of antibiotic administration was 5 days for ciprofloxacin as many as 20 patients (67%). Conclusion: The most frequently used antibiotic at the Kotaraja Publical Center is Ciprofloxcacin
Ekstraksi dan Identifikasi Metabolit Sekunder Tanaman Obat sebagai Antimalaria di Kabupaten Keerom Dehi, Rosita Irianti; Iriani, Fitriah Ardiawijianti; Damar, Alpha Christyananda
JURNAL RISET RUMPUN ILMU KEDOKTERAN Vol. 4 No. 1 (2025): April : Jurnal Riset Rumpun Ilmu Kedokteran
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrike.v4i1.5699

Abstract

Malaria remains a significant public health issue in Indonesia, particularly in endemic areas such as Keerom Regency, Papua. Efforts to control this disease face challenges due to Plasmodium resistance to synthetic drugs, highlighting the need for safer and more effective alternative treatments. This study aims to identify the secondary metabolite content of several local plants traditionally used as antimalarial remedies. An experimental laboratory study was conducted using phytochemical screening methods. The plants examined included turmeric rhizome (Curcuma longa), meniran leaves (Phyllanthus niruri), papaya leaves (Carica papaya), sambiloto (Andrographis paniculata), and brotowali (Tinospora crispa). Extraction was carried out using the maceration method with 96% ethanol as the solvent. The results showed that all samples contained secondary metabolites such as flavonoids, alkaloids, tannins, and saponins, which are known for their antiplasmodial activity. Extract yields ranged from 18% to 24%, with turmeric rhizome showing the highest yield. These findings suggest that local plants from Keerom Regency hold potential as raw materials for the development of herbal antimalarial drugs. This study serves as a preliminary step for further in vitro and in vivo bioactivity testing.