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All Journal Health Information : Jurnal Penelitian Eduvest - Journal of Universal Studies
Efrany, Erics
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Aerospace Engineering Computer Science & IT Dentistry Health Professions Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

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Aspirin Dan Kalsium Pada Pencegahan Preeklampsia : Literatur Review Abdiwijoyo, Mario; Efrany, Erics; Adhirajasa, Farhan; Putri Arinda, Tasya Wahyu; Saputra, Hans
Health Information : Jurnal Penelitian Content Digitized
Publisher : Poltekkes Kemenkes Kendari

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Abstract

Preeklampsia merupakan kondisi patologis kehamilan yang menyebabkan komplikasi serta kematian maternal maupun perinatal. Preeklampsia sendiri merupakan bagian dari hipertensi dalam kehamilan, yang telah menyebabkan kematian ibu sebesar 1.077 kasus pada tahun 2021 di Indonesia. Meskipun beberapa jurnal telah merekomendasikan penggunaan aspirin dan suplementasi kalsium untuk menurunkan insidensi preeklampsia, akan tetapi hal tersebut masih menjadi kontroversi di antara klinisi. Literature review ini bertujuan untuk mengevaluasi potensi pemberian aspirin dengan suplementasi kalsium dalam penurunan insidensi preeklampsia. Database yang digunakan pada penelitian ini antara lain Pubmed, Google Scholar, Ebsco, Medline, Science Direct, Cochrane dan Hindawi. Beberapa studi membuktikan bahwa pemberian aspirin dosis rendah dengan tidak melebihi 150mg/hari pada awal usia gestasi dapat menurunkan faktor resiko preeklampsia dan mengurangi insidensi kematian maternal dan perinatal. Pemberian suplementasi kalsium menurunkan insidensi preeklampsia pada ibu dengan defisiensi kalsium. Pemberian aspirin dosis rendah dan suplementasi kalsium sejak usia gestasi dini terbukti menurunkan insidensi preeklampsia.
Ruptured Ectopic Pregnancy with Levonorgestrel Implant : A Contraceptive Failure and Life-threatening Case Efrany, Erics; Pratiwi, Ketut Mira Yoga; Adiguna Dira, I Gede Mahendra; Widiabdi Husada, I Made Oka; Hartono, Dianawati
Eduvest - Journal of Universal Studies Vol. 5 No. 6 (2025): Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v5i6.51323

Abstract

Levonorgestrel implant is the most used in Indonesia, it is free provided by BKKBN. Levonorgestrel implant provides 99.95% of effectiveness. However, it could not prevent pregnancy absolutely including ectopic pregnancy. Ectopic pregnancy is a life threatening condition that is oftenly ignored by the patient and sometimes misdiagnosed. The incidence of ectopic pregnancy is very low, particularly in implant contraceptive users. Despite this fact, little is known about mechanism of implant failure including its correlation to ectopic pregnancy, and studies are limited. This case report presented a levonorgestrel implant contraceptive failure result in ectopic pregnancy. A 21-years-old woman P1001 was provided with levonorgestrel implant seventh month before admission. Patient was presented to emergency department after suffering from severe lower abdominal pain. She was diagnosed with ruptured ectopic pregnancy and underwent exploratory laparotomy. Her ruptured right fallopian tube was ligated and partially removed. Histopathological examination supported the diagnosis, chorionic villi lined with syncytiotrophoblast and cytotrophoblast cells in right fallopian tube tissue were found.  The levonorgestrel implant was removed and she was scheduled for next contraceptive counseling. This case report emphasizes the fact that low incidence of contraceptive implant failure, does not rule out the possibility of ectopic pregnancy. Several hypotheses have been proposed as the cause of ectopic pregnancy. Further research is necessary to determine definitive etiology in ectopic pregnancy with levonorgestrel implant contraceptive failure.
Co-Authors Abdiwijoyo, Mario Adhirajasa, Farhan Adiguna Dira, I Gede Mahendra Hartono, Dianawati Pratiwi, Ketut Mira Yoga Putri Arinda, Tasya Wahyu Saputra, Hans Widiabdi Husada, I Made Oka