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Sindrom POEMS: Tinjauan Komprehensif Terkini Teresia, Vira; Efranisa S B, Ririn; Alvionita Wongso, Clara; Geraldine Arliska, Vira; Setio, Lisa
Health Information : Jurnal Penelitian Content Digitized
Publisher : Poltekkes Kemenkes Kendari

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Abstract

Latar Belakang: Sindrom POEMS meliputi polineuropati, organomegali, endokrinopati, protein M, dan perubahan kulit. Sindrom POEMS merupakan kelainan langka dengan usia rata-rata onset antara 46 dan 56 tahun. Sindrom POEMS progresif dapat mengakibatkan gangguan kardiorespirasi berat, pada beberapa pasien dapat mengakibatkan kematian dini. Diperlukan diagnosis dan tatalaksana dini serta agresif. Tujuan: ulasan terkini yang menjelaskan sindrom POEMS belum banyak dijumpai, sehingga penulis ingin menyatukan berbagai literatur terkait serta memberikan referensi terbaru terkait sindrom POEMS. Metode: Berbagai literatur terkait diambil dalam kurun waktu 3 (tiga) tahun menggunakan database Google Scholar, PubMed, Cochrane Library dengan kata kunci “POEMS Syndrome”. Analisis dan penyusunan studi dilakukan setelah memenuhi kriteria inklusi dan kriteria eksklusi. Hasil: Sindrom POEMS adalah sindrom paraneoplastik yang langka karena kelainan sel plasma yang mendasarinya. Neuropati yang merupakan karakteristik utama dan kriteria penting untuk diagnosis. Kriteria Diagnostik Sindrom POEMS dapat digunakan untuk membantu menegakan diagnosis. Kesimpulan: Diagnosis yang tepat dapat memberikan tatalaksana yang sesuai sehingga didapatkan hasil klinis jangka panjang yang baik.
Rupture of the lacrimal saccus of occuli sinistra with rupture of the palpebra occuli sinistra Teresia, Vira; Nila Juwita, Oktarina
Science Midwifery Vol 11 No 5 (2023): December
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v11i5.1393

Abstract

This research aims to analyze the case of rupture of lacrimal sac occuli sinistra with rupture of the palpebra occuli sinitra. The research method used qualitative with a case study approach. Data collection was carried out using primary and secondary methods. Primary was carried out through direct observation, while secondary data was obtained through journal literature and books. Case illustration: a 58 years old woman complained of pain in her left eye ± 1 day ago due to a traffic accident, that was a motorbike collision accompanied by lacerations and bleeding in the lower eyelid near the nose. Physical examination revealed that the patient appeared moderately ill, composmentis, GCS 15, blood pressure: 160/90 mmHg, pulse frequency: 70x/minute, respiratory frequency: 20x/minute, temperature: 36,80 C, and BMI: 23,4 kg/m2 is overweight. Physical examination of the eyes superior and inferior eyelids have edema (+), tenderness (+). In the lacrimal punctum, there was a tear in the vertical direction measuring ± 1.5 cm and bleeding. The palpebral fissure is the horizontal size = 30 mm and the vertical = 7 mm. The patient's treatment was planned to involve recanalization of the lacrimal sac occuli sinitra accompanied by palpebral hecting under general anesthesia. The 0.5% optiflox (levofloxacin 1 mg) eye drops were administered 1 drop/hour OS, methylprednisolone 3 x 4 mg tablets PO, levofloxacin 1 x 500 mg tablet PO, and amlodipine 1 x 10 mg tablet. This case report shows that rupture of lacrimal sac occuli sinistra and rupture of the palpebra occuli sinitra occurred due to indirect blunt trauma. Complications can be prevented by carrying out appropriate management and control of risk factors.