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All Journal Klinik: Jurnal Ilmiah Kedokteran dan Kesehatan Jurnal An-Najat: Jurnal Ilmu Farmasi dan Kesehatan
Andita Nur Wijayanti
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Dentistry Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

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Profil Peresepan Obat Antituberkulosis Pasien Rawat Jalan Di Rumah Sakit “X” Kota Surabaya Vidya Kartikaningrum; Diah Nurcahyani; Andita Nur Wijayanti; Hervina Kusuma Dewi
Jurnal Ilmiah Kedokteran dan Kesehatan Vol 1 No 1 (2022): Januari: Jurnal Ilmiah Kedokteran dan Kesehatan
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/klinik.v1i1.2248

Abstract

Tuberculosis (TB) is an infectious disease caused by infection with the bacteria Mycobacterium tuberculosis that attacks the lungs or other organs of the body. The availability of antituberculosis drugs is an important thing related to the success or failure of treatment. The purpose of this study was to determine the profile of antituberculosis drug prescribing in outpatients with a diagnosis of tuberculosis at Hospital X Surabaya for the period January - June 2021. This study used an observational research type using descriptive analysis, data collection was carried out retrospectively, namely by taking secondary data through prescription sheets for patients diagnosed with tuberculosis containing antituberculosis at Hospital X Surabaya using a random sampling technique from a total of 770 prescriptions. Based on the research results, it can be seen that the most widely prescribed antituberculosis drugs are the generic drug rifampin 600 mg (17%) and the patent drug pehadoxin forte (26%). The use of combination antituberculosis was 90,63% and single therapy was 9,37%.
Pengaruh Pemberian Ekstrak Daun Sirsak (Annona Muricata L) Sebagai Antihiperglikemia Terhadap Mencit Yang Diinduksi Glukosa Andita Nur Wijayanti; Anik Dwi Wulandari
An-Najat Vol. 1 No. 4 (2023): NOVEMBER : An-Najat: Jurnal Ilmu Farmasi dan Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/an-najat.v1i4.876

Abstract

Hiperglikemia merupakan kondisi dimana terjadinya peningkatan gula darah yang signifikan dan jika tidak dikontrol secara rutin dapat menyebabkan diabetes melitus. Tanaman sirsak (Annona muricata L) secara empiris dapat mengobati penyakit diabetes, terutama daunnya. Daun sirsak mengandung senyawa saponin, flavonoid, protein, karbohidrat, alkaloid, glikosida, dan tanin. Tujuan dalam penelitian untuk mengetahui pengaruh pemberian ekstrak daun (Annona muricata L) sebagai antihiperglikemia pada mencit yang diinduksi glukosa. Penelitian ini menggunakan metode eksperimental dengan bentuk penelitian pretest-posttest control group design menggunakan 20 ekor mencit yang dibagi dalam 5 kelompok uji yaitu kontrol negatif diberi Na CMC 0,5%, kontrol positif diberi glibenklamide dosis 0,65 mg/kgBB, kelompok perlakuan yang diberi ekstrak etanol daun sirsak dosis 250 mg/kgBB, dosis 500 mg/kgBB dan dosis 750 mg/kgBB. Hewan uji dipuasakan terlebih dahulu selama 12 jam dengan tetap diberi air minum lalu diukur kadar glukosa darah puasa dengan menggunakan glukometer kemudian mencit diinduksi glukosa 20% agar mencit mengalami hiperglikemik (˃126 mg/dl). Hasil penelitian menunjukkan bahwa ekstrak etanol daun sirsak mampu menurunkan kadar glukosa darah pada mencit hiperglikemik dengan penurunan rata-rata ekstrak dosis 250 mg/kgBB sebesar 62 ± 12,86 mg/dl, dosis 500 mg/kgBB sebesar 66 ± 8,12 mg/dl, dan dosis 750 mg/kgBB sebesar 69,25 ± 11,17 mg/dl.
Profil Penyimpanan Obat High Alert Di Instalasi Farmasi Rumah Sakit Islam At-Tin Husada Ngawi Tahun 2023 Erika Aulia; Andita Nur Wijayanti; Diah Nurcahyani
An-Najat Vol. 2 No. 2 (2024): MEI : An-Najat: Jurnal Ilmu Farmasi dan Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/an-najat.v2i2.1341

Abstract

High alert medicines are medicines that require extra vigilance as they may cause serious harm if stored or labelled incorrectly. For this reason, these medicines need to be properly monitored and managed. The objective of this study is to assess whether the management of high alert medicines in the pharmacy of Attin Husada Islamic Hospital, Ngawi Province complies with standard operating procedures (SOPs). The study employs an observational approach to assess the storage of high alert medicines against the indicators listed in the SOP compliance checklist using direct observation techniques. The study results show that the storage compliance rate of high alert medicines in the pharmacy of Attin Husada Islamic Hospital is 90,34%, considered good, and the labelling compliance rate is 57,24%, considered fair and classified as well.
Co-Authors Anik Dwi Wulandari Erika Aulia Hervina Kusuma Dewi Nurcahyani, Diah Vidya Kartikaningrum