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All Journal Klinik: Jurnal Ilmiah Kedokteran dan Kesehatan Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Zefanya G. Pandelaki
Unknown Affiliation
Health Professions Medicine & Pharmacology Public Health

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Peranan Sekuen Susceptibility Weight Imaging (SWI) Pada Pemeriksaan MRI Brain Pada Kasus Tumor Zefanya G. Pandelaki; Mohammad Agus Pribowo; Ni Putu Rita Jeniyanthi
Jurnal Ilmiah Kedokteran dan Kesehatan Vol 3 No 1 (2024): Januari : Jurnal Ilmiah Kedokteran dan Kesehatan
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/klinik.v3i1.2506

Abstract

The aim of the research is to find out the role of the transverse suspectibility weighted imaging (SWI) sequence in brain MRI examination techniques in tumor cases. The research method used in this research is a qualitative descriptive study that uses a literature study approach to explore, analyze and identify information about how the Susceptibility Weighted Imaging (SWI) sequence plays a role in the Brain MRI examination process in patients who have tumors. The results and discussion of the literature review show: 1) Susceptibility-Weighted Imaging (SWI) on MRI brain has an important role in detecting blood degradation products, calcification and iron accumulation in glioblastoma. SWI allows visualization of small blood vessels, detection of iron, as well as identification of areas of calcification within the tumor, providing a more detailed picture of the nature and malignancy of glioblastoma. The Intratumoral Susceptibility Signal (ITSS) on SWI images is a visual marker associated with microhemorrhage, neoangiogenesis, and calcification, enabling tumor grading based on the frequency and distribution of these signals. In addition, Intralesional Susceptibility Signal (ILSS) also has an important role in differentiating glioblastoma from abscesses and metastases, with high levels of ILSS tending to be associated with tumor severity. Thus, the integration of SWI and ITSS and ILSS analysis can make a significant contribution to the characterization and assessment of the level of malignancy. 2) Susceptibility-Weighted Imaging (SWI) in the diagnosis of glioblastoma has the advantage of providing internal visualization of the tumor with high resolution. SWI is highly sensitive to differences in tissue susceptibility, allows the detection of neovascularization, hemorrhage, and calcification within glioblastoma, and provides detailed information about cerebral vascular anatomy. The advantages of SWI include its ability to image the Intratumoral Susceptibility Signal (ITSS) and Intralesional Susceptibility Signal (ILSS) and increase the visibility of low signal intensity structures. However, its shortcomings, namely sensitivity to artifacts, dependence on susceptibility phenomena, and subjective interpretation are aspects that need to be considered.
Peranan Sekuen Diffusion Weighted Imaging (DWI) Pada Pemeriksaan MRI Soft Tissue Leher Kasus Kanker Nasofaring (Studi Literatur) Zefanya G. Pandelaki; Annila Suryo Saputro; Ni Putu Rita Jeniyanthi
Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Vol. 4 No. 1 (2024): Maret : Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jikki.v4i1.2638

Abstract

The aim of this research is to determine the role of the Diffusion Weighted Imaging (DWI) sequence in Soft Tissue MRI examinations of the neck in cases of nasopharyngeal cancer and to determine the advantages of using the Diffusion Weighted Imaging (DWI) sequence in MRI Soft Tissue examinations of the neck in cases of nasopharyngeal cancer. The research method used was a descriptive qualitative research method with a literature study method. The results of the literature review research showed: 1) Nasopharyngeal cancer, especially squamous cell carcinoma, can be treated with radiation therapy where treatment failure is still a serious problem, especially in advanced cases. DWI and ADC are imaging methods that utilize the movement of water inside. DWI provides additional information regarding response to treatment in hard-to-reach cases of nasopharyngeal cancer. plays an important role in detection, evaluation of response to treatment, and early monitoring of chemoradiotherapy therapy. DWI also provides information that helps distinguish between tissue experiencing post-RTH fibrosis and areas that may contain active cancer cells. DWI and ADC are also useful in tumor staging, delineation of target volumes, and detection of tumor recurrence. Elevated ADC may be indicative of a favorable response to therapy, whereas low pretreatment ADC values ​​may predict a favorable response. In the diagnosis of nasopharyngeal cancer, DWI and ADC also help differentiate squamous cell carcinoma subtypes, predict response to chemoradiation therapy, and determine the appropriate time for alternative treatment regimens. 2) DWI and ADC provide advantages in the diagnosis and monitoring of nasopharyngeal cancer. DWI can image restrictions on water diffusion within tissue, helping to detect areas of high cell density associated with tumors. Its advantages include sensitivity to microenvironmental changes and the ability to early identify recurrence or secondary cancer post-radiation therapy.
Peranan Sekuen Diffusion Weighted Imaging (DWI) Pada Pemeriksaan MRI Soft Tissue Leher Kasus Kanker Nasofaring (Studi Literatur) Zefanya G. Pandelaki; Annila Suryo Saputro; Ni Putu Rita Jeniyanthi
Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Vol. 4 No. 1 (2024): Maret : Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jikki.v4i1.2638

Abstract

The aim of this research is to determine the role of the Diffusion Weighted Imaging (DWI) sequence in Soft Tissue MRI examinations of the neck in cases of nasopharyngeal cancer and to determine the advantages of using the Diffusion Weighted Imaging (DWI) sequence in MRI Soft Tissue examinations of the neck in cases of nasopharyngeal cancer. The research method used was a descriptive qualitative research method with a literature study method. The results of the literature review research showed: 1) Nasopharyngeal cancer, especially squamous cell carcinoma, can be treated with radiation therapy where treatment failure is still a serious problem, especially in advanced cases. DWI and ADC are imaging methods that utilize the movement of water inside. DWI provides additional information regarding response to treatment in hard-to-reach cases of nasopharyngeal cancer. plays an important role in detection, evaluation of response to treatment, and early monitoring of chemoradiotherapy therapy. DWI also provides information that helps distinguish between tissue experiencing post-RTH fibrosis and areas that may contain active cancer cells. DWI and ADC are also useful in tumor staging, delineation of target volumes, and detection of tumor recurrence. Elevated ADC may be indicative of a favorable response to therapy, whereas low pretreatment ADC values ​​may predict a favorable response. In the diagnosis of nasopharyngeal cancer, DWI and ADC also help differentiate squamous cell carcinoma subtypes, predict response to chemoradiation therapy, and determine the appropriate time for alternative treatment regimens. 2) DWI and ADC provide advantages in the diagnosis and monitoring of nasopharyngeal cancer. DWI can image restrictions on water diffusion within tissue, helping to detect areas of high cell density associated with tumors. Its advantages include sensitivity to microenvironmental changes and the ability to early identify recurrence or secondary cancer post-radiation therapy.
Co-Authors Annila Suryo Saputro Mohammad Agus Pribowo Ni Putu Rita Jeniyanthi