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Journal : Klinik: Jurnal Ilmiah Kedokteran dan Kesehatan

Analisis Hasil Pemeriksaan Viral Load Dan CD4 Pada Penderita HIV Di RSUD Pandan Arang Boyolali Periode Tahun 2022 Wirna Sari; Farida Noor Irfani
Jurnal Ilmiah Kedokteran dan Kesehatan Vol 3 No 1 (2024): Januari : Jurnal Ilmiah Kedokteran dan Kesehatan
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/klinik.v3i1.2630

Abstract

Acquired Immunodeficiency Syndrome disease cause HIV. This disease damages the body's immune system known as CD4. CD4 lymphocyte count is associated with disease progression, increased opportunism, and mortality. Laboratory examination required to determine the CD4 count using this method flowcytometry, and test viralload PCR method. The of research is analyze results of viralload and CD4 in HIV sufferers at RSUD Boyolali . Quantitative research method with analytical descriptive design. Data univariate and bivariate with the chi-square test to see the magnitude of relationship between the independent variables and HIV infection. total of 94 patients in 2022 showed several normal and abnormal results, where values ​​were normal viralload <10,000copy/ml low, >100,000copy/ml high, and <40copy/ml not detected. Normal CD4 results 410 – 1,600 cells/ml and low <500 cells/ml. CD4 research results and viralload normal 43 (46%) patients, CD4 results and viralload abnormal in about 9 (9%), and 1% of patients with normal CD4 countsviral load abnormal patient has not received treatment. CD4 examination uses the method flowcytometry whereas viral load using the PCR method and blood plasma samples. There is relationship viralload method PCR dan CD4 method flowcytrometry with significance value of 0.013. Further research needs to be carried out using experimental methods.
Pemeriksaan Imunologi Terhadap Kadar Hormon Thyroid Stimulating Hormone (TSH) Pada Pasien Gangguan Tiroid Di RSUD Panembahan Senopati Periode 2020-2022 Rifka Aulia Astuti; Farida Noor Irfani
Jurnal Ilmiah Kedokteran dan Kesehatan Vol 3 No 1 (2024): Januari : Jurnal Ilmiah Kedokteran dan Kesehatan
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/klinik.v3i1.2631

Abstract

Thyroid disorders are conditions of abnormalities in thyroid gland. According to function, thyroid disorders are divided into three, hyperthyroidism, hypothyroidism and euthyroidism. To detect thyroid disorders, can use laboratory test examination of TSH (Thyroid Stimulating Hormone) hormone. The aim is to determine the description of TSH levels checked periodically in patients with thyroid disorders using immunological methods. Research method is a case series method or case-by-case using secondary data from TSH hormone examination results in 2020-2022. The results were from 93 respondents based on age showed that 20-30 years old 11.8%, 31-40 years old 26.9%, 41-50 years old 26.9% and 51-60 years old 34.4%. Based on gender, 20.4% were male and 79.6% were female. Then we looked at changes in TSH hormone in patients with thyroid disorders by randomization 10 respondents. It was found that the changes were caused by consumption of anti-thyroid drugs, Thiamazole, Propranolol, Thyrozol, Propylthiouracil, Levothyroxine. Respondents with thyroid disorders were mostly found in 51-60 years and were female. There are changes in TSH hormone levels in patients with thyroid disorders were anti-thyroid drugs. The immunological method used ECLIA (Electrochemiluminescence Immunoassay) method. Factors that influence examination are the condition of sample and patient.