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All Journal Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences Biology, Medicine, & Natural Product Chemistry
Adekilekun, Habeebulahi Ajibola
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Environmental Science Medicine & Pharmacology Public Health

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An Overview of Traditional Medicinal Plants Used in Treating Hepatocellular Carcinoma (HCC) with Emphasis on Mechanisms of Action: Traditional Medicinal Treatment of Hepatocellular Carcinoma (HCC) Adekilekun, Habeebulahi Ajibola; Oyewusi, Habeebat A.; Odoma, Saidi; Kirimuhuzya, Claude
Journal of Tropical Life Science Vol. 14 No. 2 (2024)
Publisher : Journal of Tropical Life Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jtls.14.02.20

Abstract

Cancer is an incurable fatal disease wreaking havoc on the population of countries either developed or developing. Hepatocellular carcinoma (HCC) is the fifth most frequent type of cancer having a poor prognosis. Globally, HCC management and treatment intervention using medicinal plants from generation to generation is rapidly increasing and remains an area of promising research. This review provided insight into medicinal plants' ethnomedicinal use, photochemistry and mechanisms of action on HCC exhibiting anti-cancer potentials subjected to scientific investigations. Furthermore, clinical, toxicity studies and detailed mechanisms of action would provide an understanding of the development of lead compounds in drug discovery and development for HCC
An Overview of Traditional Medicinal Plants Used in Treating Hepatocellular Carcinoma (HCC) with Emphasis on Mechanisms of Action: Traditional Medicinal Treatment of Hepatocellular Carcinoma (HCC) Adekilekun, Habeebulahi Ajibola; Oyewusi, Habeebat A.; Odoma, Saidi; Kirimuhuzya, Claude
Journal of Tropical Life Science Vol. 14 No. 2 (2024)
Publisher : Journal of Tropical Life Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jtls.14.02.20

Abstract

Cancer is an incurable fatal disease wreaking havoc on the population of countries either developed or developing. Hepatocellular carcinoma (HCC) is the fifth most frequent type of cancer having a poor prognosis. Globally, HCC management and treatment intervention using medicinal plants from generation to generation is rapidly increasing and remains an area of promising research. This review provided insight into medicinal plants' ethnomedicinal use, photochemistry and mechanisms of action on HCC exhibiting anti-cancer potentials subjected to scientific investigations. Furthermore, clinical, toxicity studies and detailed mechanisms of action would provide an understanding of the development of lead compounds in drug discovery and development for HCC
Fatty Acids and Its Derivatives from the Extracts of Ficus mucoso Leaves Hamid, Abdulmumeen Amao; Egharevba, Godshelp Osas; Issa, Shuaib Bolaji; Olalere, Oluwafeyikemi Mercy; Akinloye, Bukunmi Temitope; Yakub, Yakub Tunde; Ibrahim, O. Sulyman; Umar, Idris; Adekilekun, Habeebulahi Ajibola; Sanusi, Idris Olatunji; Ahmad, Abdullahi Alhaji
Biology, Medicine, & Natural Product Chemistry Vol 15, No 1 (2026)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2026.151.151-157

Abstract

The n-hexane, ethyl acetate and methanol extracts of Ficus mucoso leaves were screened for the presence of metabolites, using column and thin-layer chromatographic techniques. Dodec-6-enoic acid (1), methyl hexadecanoate (2), hexadec-9-enoic acid (3), and ethyl tetradecanoate (4) were obtained from the extracts of F. mucoso leaves. These compounds were confirmed via 1H and 13C Nuclear Magnetic Resonance Spectroscopy (NMR) and available published literature.
Co-Authors Ahmad, Abdullahi Alhaji Akinloye, Bukunmi Temitope Egharevba, Godshelp Osas Hamid, Abdulmumeen Amao Ibrahim, O. Sulyman Idris Umar, Idris Issa, Shuaib Bolaji Kirimuhuzya, Claude Odoma, Saidi Olalere, Oluwafeyikemi Mercy Oyewusi, Habeebat A. Sanusi, Idris Olatunji Yakub, Yakub Tunde