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Intoxication Due to Consumption of Boiled Datura Stramonium (Kecubung) Leaves Gede Indra Dananjaya, Putu; Made Putri Purnama Dewi, Ni
International Journal of Advanced Multidisciplinary Vol. 3 No. 2 (2024): International Journal of Advanced Multidisciplinary (July-September 2024)
Publisher : Green Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.38035/ijam.v3i2.628

Abstract

Datura stramonium has medicinal properties that make it suitable for treating respiratory system conditions, haemorrhoids, dermatological, for treating dental infections and toothache, skin infections, alopecia, decreasing abdomen colicky pain, and also to reduce pain. When it affects the central nervous system, it can lead to delirium symptoms such as restlessness, agitation, hallucination, convulsion, coma, and even death. Case Report: We report the case of a 59 years old, female, drink 3 glasses of boiled water of Datura stramonium leaves to reduce the pain in her waist, then she appears to be hallucinating by talking to herself. Pupil showed bilateral mydriasis. The patient got 500 cc of 0.9% NaCl in 1 hour and oxygenation. After 5 hours, the patient regained consciousness. Discussion: The presence of mydriasis, is a common symptom in nearly all cases of anti-cholinergic intoxication, including Datura stramonium. Fever and erythema may occur due to vasodilation and the inhibition of sweat glands. Additional symptoms that may occur in instances of Datura intoxication include visual hallucinations. Onset of symptoms may occur within 30-60 minutes following exposure. For the majority of patients, this condition resolves spontaneously without intervention and does not pose a risk to their lives. In severe case have resulted in respiratory failure and circulatory collapse, as well as cases of rhabdomyolysis and fulminant hepatitis. Conclusion: A comprehensive medical history and understanding of the signs and symptoms that may indicate Datura stramonium intoxication are necessary. Physostigmine, a type of cholinesterase inhibitor, is effective for treating severe case.
Rhupus Syndrom in a Young Male Patient: A Rare Case Gede Indra Dananjaya, Putu; Made Putri Purnama Dewi, Ni
International Journal of Psychology and Health Science Vol. 2 No. 3 (2024): International Journal of Psychology and Health Science (July - September 2024)
Publisher : Greenation Publisher & Yayasan Global Research National

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.38035/ijphs.v2i3.626

Abstract

Rhupus syndrome refers to the simultaneous presence of systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). Rhupus syndrome exhibits a higher prevalence in female and rarely in male, similar to systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). Upon examining the literature, it is evident that the majority of case reports consist of female patients. This case report describes a male patient who diagnosed with rhupus syndrome. Case Report: We report the case of a 27-year-old male patient who based on the SLE-SLICC 2012 criteria, the patient met the diagnosis criteria of SLE. Based on the 2010 ACR/EULAR criteria, the patient was diagnosed with rheumatoid arthritis with a total score of 9. The joint criteria showed involvement of more than 10 joints with at least 1 large joint, positive rheumatoid factor results, high CRP and ESR levels, and symptom duration of more than 6 weeks. Discussion: Rhupus syndrome is a condition characterized by a symmetric polyarthritis which leads to deformation and erosion. It is preceded by symptoms and signs of SLE and the presence of antibodies that are very specific for diagnosis, such as anti-double stranded DNA, anti-Smith, and anti-cyclic citrullinated peptide. Conclusion: In this case, the timely detection of rhupus syndrome is crucial in order to select appropriate treatments, minimize potential complications, and enhance the patient's prognosis, despite its rarity.