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All Journal Malang Respiratory Journal Jambura Medical and Health Science Journal
Gubali, Winansih
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Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Other

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Rare Case of Primary Effusion Lymphoma mimicking Pulmonary Tuberculosis Idris, Dewinsya Medisujiannisa; Gubali, Winansih
Jambura Medical and Health Science Journal Vol 3, No 1 (2024): Jambura Medical and Health Science Journal
Publisher : Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37905/jmhsj.v3i1.21822

Abstract

Primary effusion lymphoma (PEL) is a rare large B-cell non-Hodgkin lymphoma (NHL) that usually occurs in immunosuppressed individuals in advanced stages of the disease, presenting as body cavity effusions without detectable tumor mass. We report a 61-years old man presented to the emergency room complaining of effort-related dyspnoea, low-grade fever, night sweats, and a dry cough for several days. He was then put on empirical anti-tubercular treatment (ATT) suspecting Pulmonary Tuberculosis. General examination revealed a decrease oxygen saturation, tachypnea, a bulging tenderness lymph node on the neck. Chest computerized tomography (CT) scan indicated pericardial and pleural effusion with mediastinal dilatation suspected thymoma or lymphoma. A Cardiocentesis needle aspiration was performed; however, the histological pattern was not specific. The patient underwent a surgical biopsy of a left supra-clavicular lymph node. A Classical Hodgkin lymphoma nodular sclerosis type was found in the histopathology examination. Immunohistochemistry detected the tumour cellular markers (i.e., CD30). Chemotherapy treatment for 6 cycles resulted an excellent outcome. In conclusion, radiologists play a vital role in the diagnosis of PEL, detecting effusions in body cavities and excluding the existence of solitary masses or pleural nodules or masses, ultimately narrowing down the differential diagnoses.
Necrotizing Pneumonia in a Child with Multiple Right Lung Abscesses: A Case Report of Challenging CT Scan Findings: English Amir, Muhajir Setiawan; Gubali, Winansih; Arfan, Andi Aisyah Nazwa Rifani; Ramadhani, Ardelia; Ismail, Mohamad Farhan
Malang Respiratory Journal Vol. 8 No. 2 (2026): Volume 8 No 2, September 2026 Edition : in Press
Publisher : Universitaas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/

Abstract

Background: Necrotizing pneumonia (NP) is a severe complication of bacterial pneumonia with progressive lung necrosis and thin-walled cavities. Rare in children, it can be fatal if not promptly treated. Chest CT is the primary imaging for diagnosis. Aim: To report an 8-year-old boy with NP and active pulmonary tuberculosis, emphasizing chest CT's diagnostic role and conservative management outcome without surgery. Methods: An 8-year-old boy presented with 2-week productive cough, fever, dyspnea, prior TB on anti-TB therapy (OAT). Examination: dullness over right lung, bilateral coarse rhonchi. Chest X-ray: right opacity with lucencies. Non-contrast chest CT: extensive right consolidation with multiple thin-walled avascular hyperlucent lesions (0.5–1 cm) and two right upper lobe abscesses (4 cm, 1.8 cm) with air-fluid levels. Left hilar retraction and left upper lobe patchy opacities indicated active TB. Treatment: IV cefotaxime, gentamicin, dexamethasone, paracetamol drip, plus continued OAT. Results: After 8 inpatient days, the patient improved and was discharged without surgery. Chest CT was crucial to differentiate NP from TB cavities and other similar conditions, despite overlapping radiological features. Conclusion: NP in children with active TB poses diagnostic challenges due to overlapping radiology. Chest CT is essential for differentiation. Early combination antibiotics with continued OAT led to favorable clinical improvement without surgical intervention. Keywords: Pediatric, Necrotizing Pneumonia, Lung Abscess, Chest CT.
Co-Authors Amir, Muhajir Setiawan Arfan, Andi Aisyah Nazwa Rifani Idris, Dewinsya Medisujiannisa Ismail, Mohamad Farhan Ramadhani, Ardelia