Yunita, Lowry
Unknown Affiliation

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

Clinical Profile of Acute Coronary Syndrome Patients in Kupang: a Result from 1-Year iSTEMI Registry Adam, Aditya Angela; Tiluata, Leonora Johana; Yunita, Lowry; Putra, Magma Purnawan; Wilujeng, Niva; Homalessy, Leonita Vivian; Hutabarat, Daniel Christian Fernandez
Jurnal Kardiologi Indonesia Vol 42 No 4 (2021): Indonesian Journal of Cardiology: October - December 2021
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.1194

Abstract

Background: Cardiovascular diseases (CVDs) have been the leading cause of global deaths over the years. In Indonesia, coronary heart disease (CHD) is the most common CVDs, responsible for 29% of all deaths in 2017. East Nusa Tenggara is one of the provinces in Indonesia with the highest prevalence of CHD, which corresponded with growing cases of acute coronary syndromes (ACS). Therefore, we develop a registry to obtain patients' profiles as a basis for strategy development in ACS management. Methods: A retrospectively observational study was conducted on all patients who presented with ACS between January 2019 and September 2020 at a general hospital in Kupang, East Nusa Tenggara. Data collected include demography, patient awareness and transfer history, risk factors, physical findings, diagnosis, workup, treatment, and mortality. Results: A total of 282 patients with ACS (STEMI, 41,2%; NSTEACS, 58,8%) were included in this study. Most patients were male with a mean age of 58,2 ± 12,2 years and normal BMI (32.6%). Nearly 50% of all ACS patients have one or more comorbidities, followed by relatively low adherence to therapy. Half of the patients were referred, but only 16,9% of patients arrived at the first medical facility less than 1 hour after onset. Patients with NTSEACS had more risk factors than patients with STEMI. The median LOS was five days (range, 1-17 days) with 2,8% in-hospital death. The presence of patient and system delay might contribute to the low number of STEMI patients who received reperfusion therapy. Conclusions: This research serves as the primary data for the improvement of acute coronary syndrome management in Kupang and East Nusa Tenggara.
Clinical Characteristics of Congenital Heart Disease in Indonesian Children with Down Syndrome: A Systematic Review and Meta-analysis Saini, Pasya Putra Pratama Ali; Yunita, Lowry; Fernandez, Sekar Andrea
Jurnal Kardiologi Indonesia Vol 47 No 1 (2026): January - March, 2026
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.1836

Abstract

Down syndrome or trisomy 21 is frequently accompanied by Congenital Heart Disease (CHD), which is a major cause of mortality and morbidity within the first two years of life in children with Down Syndrome (DS). This systematic review and meta-analysis aimed to analyze the literature to assess the pooled prevalence of overall CHDs among children with DS in Indonesia. The search was conducted across major databases, including PubMed, Google Scholar, ScienceDirect, Cochrane, and Garuda (an Indonesian database), using Boolean operators and a range of keywords. Citation management was performed using the Rayyan Intelligent Systematic Reviews website (https://www.rayyan.ai/). Quantitative data synthesis was conducted using Comprehensive Meta-Analysis version 4.0 (Biostat, Englewood, NJ, USA). Initially, 1,915 citations were retrieved from the primary search; after screening titles and assessing full texts, a total of 11 articles were included in this study. A total of 1,122 subjects from 11 different studies were analyzed. The overall pooled prevalence of CHDs among children with DS was 44.6% (95% CI: 34.9% to 54.8%). We also found a high degree of heterogeneity between the studies (I² = 88.8%), and inspection of the forest plot revealed that the distribution of the plotted data was asymmetrical. Approximately one in two children with DS in Indonesia has at least one type of CHD. These findings highlight the need for early routine cardiac screening to reduce morbidity and mortality. We recommend further research to provide more data to assess the prevalence of CHD.