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Rout, M
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Medicine & Pharmacology

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EXPLORATION OF ANTI-EPILEPTIC PROPERTY OF METHANOLIC EXTRACTION OF OCIMUM BASILICUM Ray, J; Rout, M; Prusty, S; Mohanty, R; Sahu, P
Journal of Global Pharma Technology Volume 16 Issue 02 (2024) February 2024
Publisher : Journal of Global Pharma Technology

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Abstract

The goal of the current investigation was to determine if a methanolic extract of Ocimum Basilicum (O.B.) leaves could protect against phenytoin induced Epilepsy. Epilepsy was studied using dosages of 400mg/kg is more effective than 200 mg/kg of methanolic extract of O.B. The extract was administered, which improved improve behavioral disturbances, oxidative stress can be reduced and antioxidant enzymes can be recovered. The results of this investigation showed that rats treated with a methanol extract of O.B. leaves have neuroprotective potential. Therefore, it can be inferred that Ocimum basilicum may be useful in the treatment of Epilepsy disease. Keywords: Ocimum Basilicum (O.B), Leaves, Phenytoin, Rat.
EXPLORATION OF ANTI-EPILEPTIC PROPERTY OF METHANOLIC EXTRACTION OF OCIMUM BASILICUM Ray, J; Rout, M; Prusty, S; Mohanty, R; Sahu, P
Journal of Global Pharma Technology Volume 16 Issue 02 (2024) February 2024
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The goal of the current investigation was to determine if a methanolic extract of Ocimum Basilicum (O.B.) leaves could protect against phenytoin induced Epilepsy. Epilepsy was studied using dosages of 400mg/kg is more effective than 200 mg/kg of methanolic extract of O.B. The extract was administered, which improved improve behavioral disturbances, oxidative stress can be reduced and antioxidant enzymes can be recovered. The results of this investigation showed that rats treated with a methanol extract of O.B. leaves have neuroprotective potential. Therefore, it can be inferred that Ocimum basilicum may be useful in the treatment of Epilepsy disease. Keywords: Ocimum Basilicum (O.B), Leaves, Phenytoin, Rat.
Co-Authors Mohanty, R Prusty, S Ray, J Sahu, P