Ardalani, Ghasem Fatahzadeh
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A SIX-MONTH STUDY OF CLINICAL SYMPTOMS, IMAGING AND OUTCOMES OF PATIENTS DIAGNOSED WITH CEREBRAL VENOUS SINUS THROMBOSIS (CVST) Ardalani, Ghasem Fatahzadeh; Pourfarzi, Farhad; Haddad, Amir
MNJ (Malang Neurology Journal) Vol. 10 No. 1 (2024): January
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2024.010.01.2

Abstract

Background: One of the unusual cause of headache and stroke is CVST with very diverse clinical manifestation. Onset of focal headache, headache with seizures, papilledema, or focal defect are some of important clinical features. Consideration of risk factors, especially the use of hormonal drugs, recent pregnancy, coagulation disorders, as well as recent infections and systemic inflammation, can lead to clinical suspicion of CVST. For early and accurate detection we can use modern MR imaging. Objective: To evaluate the clinical symptoms and imaging findings of patients with a diagnosis of CVST during 6-months follow-up. Methods: This cross-sectional study was used on 56 patients with CVST. Clinical, preclinical, and imaging records of inpatients and also information like age, sex, and underlying diseases were collected at a checklist.  After 6 months from the start of treatment, the identified patients were followed up through a telephone interview, and if there were any positive symptoms, they were visited on an outpatient basis in the neurology clinic of Alavi Hospital in Ardabil, and the necessary information was extracted. Collected data were analyzed by statistical methods in SPSS version 21. Results: Of all patients, 47 (84%) were women. The most common symptom was headache with 87.5% and then nausea and vomiting, sensory and visual symptoms with 57.1%, 51.8% and 44.6%, respectively. Conclusion: The results of this study showed that, the clinical symptoms of patients are very various and misleading, but the most common clinical symptoms were headache, nausea and vomiting. Women were involved more than men. The results of the study disclosed that CVST had wide range of clinical manifestations and non-specific symptoms at the beginning. For that reason, in especially high risk groups for thrombosis, the diagnosis of CVST should be kept in mind.
MAGNETIC RESONANCE IMAGING FINDINGS IN SEIZURE PATIENTS WITH NORMAL NEUROLOGICAL EXAMINATION Ardalani, Ghasem Fatahzadeh; Anari, Hasan; Sadegiyeh-Ahari, Saeed; Rezvanipour, Hossein
MNJ (Malang Neurology Journal) Vol. 10 No. 1 (2024): January
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2024.010.01.5

Abstract

Background: Imaging plays a critical role in the treatment and diagnosis of individuals experiencing seizures, particularly those whose seizures cannot be explained. In various circumstances, CT scans and MRIs (Magnetic Resonance Imaging) are utilized in tandem. Objective: The purpose of this research was to evaluate the MRI findings of patients referred to Alavi Hospital with seizures and a normal neurological examination. Methods: This case-series study examined one hundred patients with epilepsy who underwent normal neurological examinations. All patients' imaging reports were meticulously examined, and any changes were documented in pre-established checklists that comprised of the following: age, gender, family history, EEG (electroencephalogram) results, neurological assessments (including motor, plantar, and tendon reflexes), and MRI findings derived from the patients' files and clinical histories. Result: In the range of 11 to 58 years, the mean age of patients was 7.46 + 32.62 years. Males comprised forty-six (46%) of the patients. In45% of the cases, a familial history of seizures was documented (n=45). Normal EEG results were obtained in 62 cases (62%). Twenty cases (20%) of abnormalities were detected on MRI, seven of which were tumor lesions, as reported by the radiologist. The imaging of the patient's brain revealed no significant correlation between the pathological findings and variables such as age, gender, or family history. No significant correlation was observed between electroencephalogram results and pathological findings on brain imaging in patients with epilepsy. Conclusion: brain imaging partially compensates for the false negatives that occur during electroencephalograms, and concurrently employing both modalities enhances the ability to diagnose underlying issues in patients experiencing seizures.