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All Journal International Journal of Public Health Science (IJPHS) IJRETINA - International Journal of Retina
Sharma, Neharika
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Health Professions Medicine & Pharmacology Public Health

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Physical fitness and its impact on psychological health during the COVID-19 lockdown Sharma, Neharika; Singh, Prabhdeep; Pore, Prasad D
International Journal of Public Health Science (IJPHS) Vol 13, No 4: December 2024
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v13i4.24248

Abstract

Both the countrywide lockdowns as well as the worldwide lockdown and social isolation norms had an immense psychological impact on the population as a consequence of the major change in lifestyle. The present study aimed to determine changes in physical activity during the second lockdown in the Indian population, and the impact of exercise on psychological health during the same time period. The study was conducted through circulation of online questionnaire and data was collected by snowball technique. The type of physical activity done by most people was under the low international physical activity questionnaire (IPAQ) category (56.36%) which increased during lockdown (63.57%). The IPAQ category of moderate activity showed a drop in numbers from 26.46% to 18.56% while high IPAQ scores were almost the same before and during lockdown. People with high and moderate IPAQ scores had a better psychological health status as compared to the Low category.
DOES BASELINE SUB-FOVEAL CHORIODAL THICKNESS DETERMINES TREATMENT RESPONSE TO INTRAVITREAL AFLIBERCEPT IN DIABETIC MACULAR EDEMA? Ranjan, Somesh; Nehra, Harshraj; Sharma, Vinod; Goel, Kashish; Kumari, Madhu; Agarwal, Sarita; Sharma, Neharika; Mehta, Bhavya; Sharma, Ram Lal; Bhargava, Rahul
International Journal of Retina Vol 7 No 1 (2024): International Journal of Retina (IJRetina) - INAVRS
Publisher : Indonesian Vitreoretinal Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35479/ijretina.2024.vol007.iss001.260

Abstract

Introduction: To determine the predictive value of baseline SFCT for response to treatment with serial intravitreal aflibercept injections for diabetic macular edema (DME). Methods: A prospective multi-center study was done. Eyes with DME (n=95) were treated with intravitreal aflibercept injections q4week for first 5 doses, followed by 2mgq8week, respectively. SFCT and central macular thickness (CMT) were measured with serial enhanced depth imaging optical coherence tomography scans done at baseline and after the last injection. A functional responder was one with >5 ETDRS letter gain in vision. An anatomical responder was one with SFCT reduction>25u. Results: At 6 months, after the last IV injection of aflibercept, the mean SFCT decreased significantly (319±47 at baseline, 250±36 at 6 months, P<0.001). A significantly higher baseline SFCT was seen in functional responders as compared to non-responders (329±50 versus 303±36u, independent t-test, P=0.002). Likewise, anatomical responders has a significantly higher baseline SFCT as compared to non-responders (327±51 versus 305±33, P=0.002). Multiple logistic regression (after adjusting for confounders like age, gender, duration of diabetes, and glycemic control, respectively) revealed that higher SFCT had increased odds of having a better functional (odds ratio=1.40, P=0.050) and anatomical outcome (odds ratio=1.23, P=0.001), respectively. The mean vision gain in functional responders and non-responders was 11and 5 ETDRS letters, respectively (P<0.001). The mean vision gain in anatomic responders and non-responders was 10 and 6 ETDRS letters, respectively (P<0.001). Conclusion: SFCT at baseline predicts response to intravitreal aflibercept therapy in DME patients after adjusting for confounders. Eyes with a thicker baseline sub-foveal choroidal thickness had better anatomic and functional response at 9 months.
Co-Authors Agarwal, Sarita Bhargava, Rahul Goel, Kashish Kumari, Madhu Mehta, Bhavya Nehra, Harshraj Pore, Prasad D Ranjan, Somesh Sharma, Ram Lal Sharma, Vinod Singh, Prabhdeep