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All Journal Journal of Degraded and Mining Lands Management The Journal of Society Medicine (JSOCMED)
Hassan, Omar
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience

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Removal of heavy metal ions from water using nanocellulose-based membranes derived from macroalgae Chara corallina Yousif, Yasir; Hassan, Omar; Ibraheem, Ibraheem J.
Journal of Degraded and Mining Lands Management Vol. 11 No. 3 (2024)
Publisher : Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15243/jdmlm.2024.113.5793

Abstract

Chara corallina is a freshwater macroalgae found in aquatic-terrestrial boundary environments. Their cellulose fibers have a crystallinity and biosynthesis similar to those of terrestrial plants. The algal nanocellulose (NC) was prepared through a series of chemical treatments, including alkaline, bleaching, grinding, and acid hydrolysis. The X-ray diffraction (XRD) crystallinity index of nanocellulose was 85.64%. The cellulose nanocrystals are seen in the form of nanorods, and the specific surface area of the sample of NC found was 5.823 m2g-1. The study aimed to test the effectiveness of a nanocellulose composite membrane in removing heavy metal ions, specifically cadmium (Cd), nickel (Ni), and lead (Pb) ions, from an aqueous solution. A vacuum filtration unit was used for the experiment, where up to five filter layers of composite membranes were examined for their ability to remove heavy metal ions. The results showed that the highest removal rates of Cd2+, Ni2+, and Pb2+ ions were 98.20%, 95.15%, and 93.80%, respectively, when using five layers of membranes of NC with the adsorbent dose set at 20 ppm. Cellulose and its derivatives are essential in sustainable technology for wastewater treatment, as they demonstrate exceptional performance in removing various types of pollutants, including heavy metals, dyes, and other pollutants. Cellulose is preferred due to its low cost, biodegradability, eco-friendliness, and simple surface modification.  
Early Fluid Resuscitation Volume as an Independent Determinant of Mortality in Sepsis: A Multicenter Real-World ICU Cohort Study El-Sayed, Amina; Hassan, Omar; Khaled, Youssef
Journal of Society Medicine Vol. 5 No. 4 (2026): April
Publisher : CoinReads Media Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71197/jsocmed.v5i4.279

Abstract

Introduction: Early intravenous fluid resuscitation is central to sepsis management; however, the optimal volume during the initial resuscitation window remains uncertain. Although current guidelines recommend at least 30 mL/kg of crystalloids within 3 h, this fixed-volume threshold may not capture the heterogeneity of septic ICU care unit. This study evaluated the association between early fluid resuscitation volume and mortality using multicenter, real-world ICU data. Methods: We conducted a retrospective multicenter cohort study using MIMIC-IV and eICU-CRD. Adult ICU patients who fulfilled the Sepsis-3 criteria were included. The primary exposure was the cumulative crystalloid volume administered within the first 3 h after sepsis onset. Fluid volume was analyzed as categorical mL/kg strata, the conventional ≥30 mL/kg threshold, and a continuous variable using restricted cubic splines. The primary outcome was in-hospital mortality. Multivariable logistic regression, propensity score weighting, and marginal structural models were used to address the baseline severity, treatment intensity, and time-varying confounding. Results: Among 18,742 septic ICU care unit, early fluid volume showed a nonlinear dose–response association with mortality. Patients receiving 20–30 mL/kg had the lowest adjusted mortality, whereas both lower-volume resuscitation (< 10 mL/kg) and liberal resuscitation (≥ 40 mL/kg) were associated with increased mortality. The ≥30 mL/kg threshold was not consistently associated with improved survival after the adjustment. The findings remained robust across sensitivity analyses, alternative exposure windows, and causal inference models. Conclusion: Early fluid resuscitation volume in patients with sepsis is associated with mortality in a non-linear, dose-dependent pattern. These findings challenge the universal applicability of fixed 30 mL/kg resuscitation and support individualized physiology-guided fluid strategies in critically ill patients with sepsis.
Co-Authors El-Sayed, Amina Ibraheem, Ibraheem J. Khaled, Youssef Yousif, Yasir